Jiebeian (azvudine) / Genuine Biotech - LARVOL DELTA

Azvudine remodels the local immunosuppressive microenvironment and exhibits sustained anti-tumor effects in combination with anti-PD-1 therapies. (PubMed, Front Med) - "FNC remodels the TME by mitigating immunosuppression and amplifying anti-tumor immunity, offering a promising strategy to augment existing immunotherapies. Further clinical evaluation is warranted to ascertain the translational potential of FNC in diverse oncologic settings."

Journal • Oncology • CALR • CD8 • HMGB1

A Phase Ⅰ Clinical Study of GEN-725 Tablets in Patients With Advanced Solid Tumors (clinicaltrials.gov) - P1 | N=48 | Recruiting | Sponsor: Henan Genuine Biotech Co., Ltd.

New P1 trial • Solid Tumor