ISD017
/ iSD Immunotech, Biogen
- LARVOL DELTA
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May 15, 2024
The STING inhibitor (ISD-017) reduces glomerulonephritis in 129.B6.Fcgr2b-deficient mice.
(PubMed, Sci Rep)
- "ISD017 reduced activated T cells and neutrophils, while cyclophosphamide targeted activated B cells. These results suggested that STING inhibitors can potentially be a new therapeutic drug for treating lupus."
Journal • Preclinical • Glomerulonephritis • Immunology • Inflammatory Arthritis • Lupus • Lupus Nephritis • Nephrology • Renal Disease • CD4 • CD69 • IL1B • STING
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