V935 Vaccine / Merck (MSD) - LARVOL DELTA

ELEKTRA: A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of TAK-935 (OV935) as an Adjunctive Therapy in Pediatric Patients With Developmental and/or Epileptic Encephalopathies (clinicaltrials.gov) - P2; N=141; Completed; Sponsor: Takeda; Active, not recruiting ➔ Completed; Trial completion date: Oct 2020 ➔ Jul 2020; Trial primary completion date: Sep 2020 ➔ Jun 2020

Clinical • Trial completion • Trial completion date • Trial primary completion date • CNS Disorders • Epilepsy • Pediatrics

A Multicenter, Open-label, Pilot Study of TAK-935 (OV935) in Participants With 15Q Duplication Syndrome or Cyclin-Dependent Kinase-Like 5 (CDKL5) Deficiency Disorder (ARCADE STUDY) (clinicaltrials.gov) - P2; N=20; Completed; Sponsor: Takeda; Active, not recruiting ➔ Completed

Clinical • Trial completion

A Multicenter, Open-label, Pilot Study of TAK-935 (OV935) in Participants With 15Q Duplication Syndrome or Cyclin-Dependent Kinase-Like 5 (CDKL5) Deficiency Disorder (ARCADE STUDY) (clinicaltrials.gov) - P2; N=20; Active, not recruiting; Sponsor: Takeda; Recruiting ➔ Active, not recruiting; N=30 ➔ 20

Clinical • Enrollment change • Enrollment closed

ELEKTRA: A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of TAK-935 (OV935) as an Adjunctive Therapy in Pediatric Patients With Developmental and/or Epileptic Encephalopathies (clinicaltrials.gov) - P2; N=141; Active, not recruiting; Sponsor: Takeda; Recruiting ➔ Active, not recruiting

Enrollment closed

Safety, tolerability and immunogenicity of V934/V935 hTERT vaccination in cancer patients with selected solid tumors: a phase I study. (PubMed, J Transl Med) - P1; "Our results suggest the safety and feasibility of V934/V935 hTERT vaccination in cancer patients with solid tumors Trial Registration Name of the registry: ClinicalTrial.gov Trial registration number: NCT00753415 Date of registration: 16 September 2008 Retrospectively registered URL of trial registry record: https://clinicaltrials.gov/ct2/results?cond=&term=NCT00753415&cntry=&state=&city=&dist=."

Clinical • Journal • P1 data