CB 5300 / Canopus BioPharma - LARVOL DELTA

Selective STAT3 Allosteric Inhibitors HCB-5300 and HCB-5400 Alleviate Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice. (PubMed, Int J Mol Sci) - "HCB-5300 and HCB-5400 are potent and selective STAT3 allosteric inhibitors with notable anti-inflammatory effects. HCB-5400's efficacy underscores its potential as a therapeutic candidate for managing inflammatory flares in IBD."

Journal • Preclinical • Gastroenterology • Gastrointestinal Disorder • Immunology • Inflammation • Inflammatory Bowel Disease • Mucositis • Ulcerative Colitis • IL6 • STAT3