Bimmugen (recombinant adsorbed hepatitis B vaccine yeast-derived) / Meiji Seika, Daiichi Sankyo - LARVOL DELTA

Hepatitis B Boosters Using a Different Product vs. the Same Product for Kidney Transplant Recipients: A Retrospective Study With Bayesian Inference. (PubMed, Clin Transplant) - "The crossover strategy hepatitis B vaccines did not appear to lead to seroconversion of much significance among KTR. Other options to augment the protection should be investigated to protect these populations against the infection."

Clinical • Journal • Retrospective data • Hepatitis B • Infectious Disease • Inflammation • Transplantation

Hepatitis B Surface Antigen Positivity Following Hepatitis B Vaccination (Bimmugen) in a Patient Undergoing Chronic Hemodialysis. (PubMed, Ther Apher Dial) - No abstract available

Journal • Hepatitis B • Infectious Disease • Inflammation

Importance of HBsAg recognition by HLA molecules as revealed by responsiveness to different hepatitis B vaccines. (PubMed, Sci Rep) - "As Bimmugen and Heptavax-II tended to have high and low vaccine responses to DRB1*13:02, 15 residues were found in the Heptavax-II-derived antigenic peptide predicted to have the most unstable HLA-peptide binding. Further functional analysis of selected hepatitis B patients with HLA haplotypes identified in this study is expected to lead to an understanding of the mechanisms underlying liver disease."

Journal • Hepatitis B • Hepatology • Infectious Disease • HLA-DRB1

Comparison of hepatitis B vaccine efficacy in Japanese students: a retrospective study. (PubMed, Environ Health Prev Med) - "Bimmugen® is associated with more effective HBs antibody production than Heptavax-II® in Japanese students. However, the Heptavax-II® vaccine is an appropriate choice for HBV vaccination in areas where HB is caused predominantly by HBV genotype C. With both vaccines, women tended to acquire more immunogenicity than men. Intramuscular injection may be the preferred administration route due to the possibility of local reactions."

Journal • Retrospective data

Acquisition rate of antibody to hepatitis B surface antigen among medical and dental students in Japan after three-dose hepatitis B vaccination. (PubMed, Vaccine) - "Anti-HBs titer decreases by an average of 20% within 4 months between the 1st and 5th month after the third dose. Therefore, anti-HBs titer should be measured periodically after completing the three-dose vaccination. Additionally, results suggested that booster doses are effective if administered with the same schedule as primary vaccination."

Journal