HY-078020 / Hefei Yigong Pharmaceutical - LARVOL DELTA

Development and Validation of an LC-MS/MS Method for the Quantification of HY-078020 in Human Plasma Using Liquid-Liquid Extraction and Its Application to Human Pharmacokinetic Study. (PubMed, Biomed Chromatogr) - "The monitored transitions were m/z 515.2 → 282.3 for HY-078020 and m/z 521.1 → 282.3 for the internal standard. Intra- and interbatch precision was within 9.03% and 5.46%, respectively, and the analyte remained stable under benchtop, freeze-thaw, processed-sample, reinjection, and long-term storage conditions. With its small plasma volume requirement, broad calibration range, low carryover, and robust stability, this method is suitable for routine quantification of HY-078020 in human plasma and may support future pharmacokinetic studies."

Journal • PK/PD data