JNJ-1661010
/ J&J
- LARVOL DELTA
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September 02, 2019
The role of spinal endocannabinoids in a rat model of oro-facial neuropathic pain
(Neuroscience 2019)
- "...The time course of analgesic effects of intrathecally administered a FAAH inhibitor JNJ1661010 and a MAGL inhibitor JZL184 were examined... The increase of spinal endocannabinoids reduced the pain-related behavior in a rat model of oro-facial neuropathic pain. The pain modulation was mediated by CB2 receptors."
Preclinical
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