BEAM-102
/ Beam Therap
- LARVOL DELTA
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August 10, 2021
Beam Therapeutics Provides Business and Pipeline Updates and Reports Second Quarter 2021 Financial Results
(GlobeNewswire)
- "Beam anticipates filing an IND for BEAM-101, which reproduces single base changes seen in individuals with Hereditary Persistence of Fetal Hemoglobin, or HPFH, to potentially protect them from the effects of mutations causing sickle cell disease (SCD), and initiating IND-enabling studies for BEAM-102, which directly corrects the causative mutation in SCD...both in the second half of 2021. Beam is also on track to nominate its first Development Candidate for in vivo base editing of the liver using LNP delivery by the end of 2021....Beam plans to present preclinical data highlighting its approach to using adenine base editing (ABE) for the treatment of sickle cell disease, including updated safety data during an oral session at the Cold Spring Harbor Laboratory’s Genome Engineering: CRISPR Frontiers Conference."
IND • Preclinical • Hematological Disorders • Sickle Cell Disease
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