BI 764122 / Boehringer Ingelheim - LARVOL DELTA

Synthesis of Potent Vanin-1 Inhibitors Labelled With Carbon-14 and Deuterium. (PubMed, J Labelled Comp Radiopharm) - "For metabolic considerations, the radioactive carbon was also incorporated in a cyclopropyl in [14C]-BI 764122 synthesis. The deuterium labelling of these three compounds was completed using the common moiety (S)-N-(methyl-d3)-N-(pyrrolidin-3-yl)acetamide-d3, which was prepared in three steps and then coupled to the corresponding aryl acids via amide bond."

Journal • Inflammation

A Study in Healthy Men to Find Out How Well Different Doses of BI 764122 Are Tolerated and Whether Food Affects the Amount of BI 764122 in the Blood (clinicaltrials.gov) - P1; N=76; Completed; Sponsor: Boehringer Ingelheim; Active, not recruiting ➔ Completed

Clinical • Trial completion

A Study in Healthy Men to Find Out How Well Different Doses of BI 764122 Are Tolerated and Whether Food Affects the Amount of BI 764122 in the Blood (clinicaltrials.gov) - P1; N=76; Active, not recruiting; Sponsor: Boehringer Ingelheim; Recruiting ➔ Active, not recruiting

Clinical • Enrollment closed