[Ac 225]RTX-2358
/ Ratio Therap
- LARVOL DELTA
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December 16, 2025
Ratio Therapeutics has Successfully Dosed the First Cohort in its Phase 1/2 Study Evaluating a Novel FAP-Targeted Radiopharmaceutical in Patients with Late-Stage Aggressive Sarcomas
(PRNewswire)
- "The ATLAS trial is a Phase 1/2 open-label clinical trial...designed to assess the safety, tolerability, dosimetry, biodistribution, pharmacokinetics, and preliminary anti-tumor activity of [Ac-225]-RTX-2358, a highly selective, FAP targeted radiotherapeutic labeled with Actinium 225, in patients with relapsed or refractory soft tissue sarcomas that express FAP."
Trial status • Soft Tissue Sarcoma
November 27, 2025
ATLAS: Actinium Therapy for Late-stage Aggressive Sarcomas
(clinicaltrials.gov)
- P1 | N=26 | Recruiting | Sponsor: Ratio Therapeutics, Inc. | Not yet recruiting ➔ Recruiting
Enrollment open • Oncology • Sarcoma • Soft Tissue Sarcoma • Solid Tumor
November 23, 2025
A PH/2 STUDY OF THE RADIOPHARMACEUTICAL [AC-225]RTX-2358 IN THE TREATMENT OF RELAPSED / REFRACTORY (R/R) SOFT TISSUE SARCOMA (STS) THE ATLAS STUDY - ACTINIUM THERAPY FOR LATE-STAGE AGGRESSIVE SARCOMAS
(CTOS 2025)
- "N/A"
Oncology • Sarcoma • Soft Tissue Sarcoma • Solid Tumor • CAFs • FAP
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