ION775
- LARVOL DELTA
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October 07, 2025
…Ionis will share positive interim Phase 1 results of ION775, an apoC-III siRNA with the potential for semiannual dosing and Ionis’ first clinical-stage siRNA medicine.
(Ionis Pharmaceuticals Press Release)
- "ION775 achieved substantial, durable and sustained reductions in apoC-III and fasting triglycerides with favorable safety and tolerability in healthy volunteers with moderately elevated triglycerides. Ionis is on track to initiate a Phase 2 study in 2026."
New P2 trial • P1 data • Severe Hypertriglyceridemia
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