NS10712 / DanPET - LARVOL DELTA

Effects of AFQ056 on language learning in fragile X syndrome. (PubMed, J Clin Invest) - P2 | "Despite the large body of evidence supporting use of mGluR5 NAMs in animal models of FXS, this study suggests that this mechanism of action does not translate into benefit for the human FXS population and that better strategies are needed to determine which mechanisms will translate from pre-clinical models to humans in genetic neurodevelopmental disorders."

Journal • CNS Disorders • Developmental Disorders • Fragile X Syndrome • Genetic Disorders • Psychiatry