sodium iodide I 131 / Generic mfg. - LARVOL DELTA

Imaging-Guided Targeted Radionuclide Tumor Therapy: From Concept to Clinical Translation. (PubMed, Adv Drug Deliv Rev) - "Since the first introduction of sodium iodide I-131 for use with thyroid patients almost 80 years ago, more than 50 radiopharmaceuticals have reached the markets for a wide range of diseases, especially cancers...This strategy leads to significantly enhanced therapeutic efficacy, improved patient outcomes, and manageable adverse events. In this review, we provide an overview of imaging-guided targeted radionuclide therapy for different tumors such as advanced prostate cancer and neuroendocrine tumors, with a focus on development of new radioligands and their preclinical and clinical results, and further discuss about challenges and future perspectives."

Journal • Review • Endocrine Cancer • Genito-urinary Cancer • Neuroendocrine Tumor • Oncology • Prostate Cancer • Solid Tumor

Anlotinib or Penpulimab in Combination With RAI for DTC (clinicaltrials.gov) - P2 | N=42 | Recruiting | Sponsor: Peking Union Medical College Hospital | Not yet recruiting ➔ Recruiting

Combination therapy • Enrollment open • Endocrine Cancer • Oncology • Solid Tumor • Thyroid Gland Carcinoma • MRI

A Randomized, Open-label Clinical Trial, Focus on the Safety and Efficacy of Anlotinib Hydrochloride in Combination With RAI in Patients With Local Advanced and Tyriod Cancer (clinicaltrials.gov) - P2; N=40; Not yet recruiting; Sponsor: Peking Union Medical College Hospital

Clinical • Combination therapy • New P2 trial • Endocrine Cancer • Oncology • Solid Tumor • Thyroid Gland Carcinoma • MRI

International Isotopes Inc. Announces Financial Results for The Second Quarter And Six-Months 2020 (PRNewswire) - "Revenue from the radiochemical products segment, which includes contact manufacturing, increased approximately 44% and 51% for the three and six-month periods ended June 30, 2020 compared to the same periods in 2019. This increase was primarily the result of sales of our new generic sodium iodide I-131 drug product which was launched in March 2020...International Isotopes Inc. manufactures a wide range of calibration and reference standards for nuclear medicine, generic sodium iodide I-131 drug product for hyperthyroidism and thyroid cancer..."

Commercial • Oncology • Thyroid Cancer

International Isotopes Inc. announces U.S. Food And Drug Administration approval of their ANDA for sodium iodide I-131 (PRNewswire) - "International Isotopes Inc....is pleased to announce it has received approval from the U.S. Food and Drug Administration (FDA) for its SODIUM IODIDE I-131 pharmaceutical product. SODIUM IODIDE I-131 is a radioactive therapeutic agent indicated for the treatment of hyperthyroidism and carcinoma of the thyroid."

ANDA