CCI-38 / City of Hope - LARVOL DELTA

City of Hope Scientists Uncover Protein That Helps Cancer Cells Dodge CAR T Cell Therapy (Businesswire) - "Scientists at City of Hope...have collared a tricky culprit that helps cancer cells evade CAR T cell therapy....The researchers identified a protein called YTHDF2 that plays a starring role in advancing the development of blood cancers. City of Hope then created a new medicinal compound called CCI-38, which targets and suppresses YTHDF2, reducing the growth of aggressive blood cancers. The approach improves the likelihood of successful cancer treatment."

New molecule • Hematological Malignancies • Oncology