PD-407824 / Weill Cornell Medical College - LARVOL DELTA

Integrative analysis of m3C associated genes reveals METTL2A as a potential oncogene in breast Cancer. (PubMed, J Transl Med) - "Through drug sensitivity analysis, Trifluridine, PD407824, and Taselisib were shown to be effective drugs for METTL2A-positive BRCA patients. Overall, our research conducts a holistic view of the expression level and prognostic signature of m3C-related genes with multiple malignancies. Importantly, METTL2A has been intensely explored as a potential oncogene in BRCA, to aid the development of potential drug agents for precision therapy in breast cancer patients."

Journal • Breast Cancer • Oncology • Solid Tumor • BRCA