BMS-986090
/ BMS
- LARVOL DELTA
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May 20, 2022
Perturbations in Podocyte Transcriptome and Biological Pathways Induced by Injury Caused by FSGS Associated Circulating Factors
(ATC 2022)
- "Charles Craik and described previously) or anti CD40 antibody (BMS 986090) was tested to reverse podocyte injury... This study provides a proof of concept that inhibition of uPAR and CD40 signaling in podocytes can be an effective treatment strategy for recurrence of FSGS and potential abrogation of FSGS disease and renal allograft salvage."
IO biomarker • Focal Segmental Glomerulosclerosis • Glomerulonephritis • Immune Modulation • Inflammation • Transplantation
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