HEC228032 / HEC Pharm - LARVOL DELTA

HEC228032, an orally bioavailable molecular glue pan-RAS (ON) inhibitor with highly potent anti-tumor efficacy (AACR 2026) - "HEC228032 is a promising pan-RAS(ON) inhibitor, characterized by potent antitumor activity against diverse RAS mutants, favorable pharmacokinetic properties, and an excellent tolerability profile, supporting its strong potential for clinical development."

Clinical • Colorectal Cancer • Lung Cancer • Non Small Cell Lung Cancer • Oncology • Pancreatic Ductal Adenocarcinoma • Solid Tumor • HRAS • KRAS • NRAS