PD-BT2238 / BioArctic - LARVOL DELTA

BioArctic expands portfolio with alpha-synuclein Brain Transporter project (PRNewswire) - "BioArctic AB...announced that the company is expanding its alpha-synuclein project portfolio. The new project, PD-BT2238, combines a selective alpha-synuclein oligomer targeting antibody with BioArctic's proprietary Brain Transporter technology, to increase exposure of the antibody in the brain, with the aim of increasing efficacy of a potential treatment in Parkinson's disease....BioArctic's aim is to develop an antibody treatment targeting soluble aggregated forms of alpha-synuclein, a protein that is genetically and neuropathologically linked to Parkinson's disease and believed to be an important initiating factor in the disease development. The PD-BT2238 project is a second-generation alpha-synuclein antibody, combining an oligomer-selective alpha-synuclein antibody with BioArctic's Brain Transporter technology, designed to improve brain exposure."

Preclinical • CNS Disorders • Parkinson's Disease