nuclomedone (SD-118) / Sino Biopharm - LARVOL DELTA

A closed-loop approach to the study of the baroreflex dynamics during posture changes at rest and at exercise in humans. (PubMed, Am J Physiol Regul Integr Comp Physiol) - "At rest, BRS was 35.1ms∙mmHg (SD17.1) in S and 16.7ms∙mmHg (SD6.4) in U (p<0.01), RRi was 901ms (SD118) in S and 749ms (SD98) in U (p<0.01), and MAP was 76mmHg (SD11) in S and 83mmHg (SD8) in U (p<0.01)...The prompt BRS decrease during up-tilt at rest may be ascribed to a vagal withdrawal, similarly to what occurs at exercise onset. The OP resetting may be due to a slower control mechanism, possibly an increase in sympathetic activity."

Journal

Outcomes of the keystone perforator island flap for oncologic reconstruction of the back. (PubMed, J Surg Oncol) - "The KPIF is a reliable and safe option for reconstruction of oncological back defects with minimal perioperative complications. This flap option avoids the use of free flaps and myocutaneous flaps for moderate-sized back defects."

Journal • Dermatology • Infectious Disease • Melanoma • Oncology • Sarcoma • Solid Tumor

Proposition of a simple binary grading of estimated blood loss during colon surgery. (PubMed, Int J Colorectal Dis) - "Anaesthesiologist and surgeon's EBL correlated with ΔHb. Simple grading of blood loss as "usual" and "more than usual" predicted severe complications and higher mortality rates. This simple binary grading of blood loss in colon surgery could be an alternative to the estimation of blood loss in ml as it is easy to apply but needs to be validated externally."

Journal • Anesthesia