TAS0286 / Otsuka, Helsinn - LARVOL DELTA

Exploring the anti-quorum sensing potential of sea anemone bacterial symbionts from Samalona Island (Spermonde Archipelago) in South Sulawesi, Indonesia. (PubMed, Antonie Van Leeuwenhoek) - "Based on the analysis of the inhibition percentage of violacein production and the percentage inhibition of biofilm formation from 105 isolates obtained from 3 species of sea anemones, there are six isolates with inhibition percentage values above 80%, namely HM12, HM19, EQ30, SG03, HM05, and EQ05...Six isolates of anemone symbionts have been identified that show the ability to produce anti-quorum sensing agents. This provides potential for effective and environmentally friendly control of pathogenic bacteria."

Journal

HMB-P-404. HMB05 Sunday Pathogen Interaction with Host Cells (ASM Microbe 2025) - "Poster viewing hours are 10:00 am - 5:00 pm. Posters will be presented twice from 10:30 am - 11:30 am and 3 pm - 4 pm at their assigned poster board."

HMB-P-203. HMB05 Friday Pathogen Interaction with Host Cells (ASM Microbe 2025) - "Poster viewing hours are 10:00 am - 5:00 pm. Posters will be presented twice from 10:30 am - 11:30 am and 4 pm - 5 pm at their assigned poster board."

Activation of DCTN1-RET Fusion Through Coiled-coil Domain as a Potential Target for RET Inhibitors. (PubMed, Anticancer Res) - "DCTN1-RET is a novel oncogenic fusion gene in thyroid cancer that promotes tumorigenesis through CC domain-mediated dimerization. It represents a potential therapeutic target for RET-specific inhibitors."

Journal • Endocrine Cancer • Gene Therapies • Lung Cancer • Oncology • Solid Tumor • Thyroid Gland Carcinoma • DCTN1 • RET

HMB-P-013. HMB05 Friday Cell Signaling Responses to Pathogens (ASM Microbe 2024) - "DESCRIPTION Poster viewing hours are 10:00 am - 5:00 pm. Posters will be presented twice from 10:30 am - 11:30 am and 4 pm - 5 pm at their assigned poster board."

P205. HMB05 Microbe Interactions with Non-mammalian Host III (ASM Microbe 2023) - "DESCRIPTION Poster viewing hours are 10:00 am - 5:00 pm. Posters will be presented twice from 10:30 am - 11:30 am and 3 pm - 4 pm at their assigned poster board."

P126. HMB05 Microbe Interactions with Non-mammalian Host (ASM Microbe 2023) - "DESCRIPTION Poster viewing hours are 10:00 am - 5:00 pm. Posters will be presented twice from 10:30 am - 11:30 am and 4 pm - 5 pm at their assigned poster board."

P052. HMB05 Microbe Interactions with Non-mammalian Host I (ASM Microbe 2023) - "DESCRIPTION Poster viewing hours are 10:00 am - 5:00 pm. Posters will be presented twice from 10:30 am - 11:30 am and 4 pm - 5 pm at their assigned poster board."

Herd level economic comparison between the shape of the lactation curve and 305 d milk production. (PubMed, Front Vet Sci) - "In conclusion, HLCC and HM305 explain the same amount of variance in IOFC-cow or IOFC-milk. HLCC is more computationally expensive, while HM305 is more readily available."

Journal

Poster. HMB05 Microbe Interactions with Non-mammalian Host II (ASM Microbe 2022) - "Poster Viewing Hours are 10:00 am - 5:00 pm. However, posters will be presented twice during Poster Presentation 1 (10:30 am - 11:30 am) and Poster Presentation 2 (4 pm - 5 pm) at their assigned poster board."

Poster. HMB05 Microbe Interactions with Non-mammalian Host I (ASM Microbe 2022) - "Poster Viewing Hours are 10:00 am - 5:00 pm. However, posters will be presented twice during Poster Presentation 1 (10:30 am - 11:30 am) and Poster Presentation 2 (4 pm - 5 pm) at their assigned poster board."

[VIRTUAL] HMBP108 - HMB05 Microbe Interactions with Non-mammalian Host (WMF 2021) - "Participants may also contact iPoster presenters using the networking tools within the digital platform. Information on accessing the iPoster Hall is available under General Information on the dashboard."

Repertoire and Diversity of Toxin - Antitoxin Systems of Crohn's Disease-Associated Adherent-Invasive Escherichia coli. New Insight of T his Emergent E. coli Pathotype. (PubMed, Front Microbiol) - "However, different transcriptional responses were detected between reference strains (NRG857c and HM605), recalling the high diversity associated to this pathotype. To our knowledge this is the first analysis of TA systems associated to AIEC and it has revealed new insight associated to this emergent E. coli pathotype."

Journal • Crohn's disease • Gastroenterology • Immunology • Inflammatory Bowel Disease

Replication of Crohn's Disease Mucosal E. coli Isolates inside Macrophages Correlates with Resistance to Superoxide and Is Dependent on Macrophage NF-kappa B Activation. (PubMed, Pathogens) - "...Gentamicin exclusion assay was used to assess E. coli replication within J774.A1 murine macrophages...Exemplar CD E. coli HM605 and LF82 were unable to survive within Nfκb1 murine bone marrow-derived macrophages. In keeping with this, pre-incubation of macrophages with hydrocortisone (0.6 µM for 24 h) caused 70.49 ± 12.11% inhibition of intra-macrophage replication...Replication correlates with resistance to superoxide and is highly dependent on macrophage NF-κB signalling. This may therefore be a good therapeutic target."

Journal