XOMA 213 / Xoma - LARVOL DELTA

Annulation of Enals with Carbamoylpropiolates via NHC-Catalyzed Enolate Pathway: Access to Functionalized Maleimides/Iso-maleimides and Synthesis of Aspergillus FH-X-213. (PubMed, J Org Chem) - "The developed protocol is mild and tolerates a wide range of substituents on both substrates. The application of this protocol in the synthesis of the antibacterial natural product Aspergillus FH-X-213 has also been demonstrated."

Journal

Phase I Study of LFA102 in Patients With Advanced Breast Cancer or Castration-resistant Prostate Cancer. (PubMed, Anticancer Res) - "Treatment with LFA102 was well tolerated."

Clinical • Journal • P1 data • Breast Cancer • Genito-urinary Cancer • Oncology • Prostate Cancer • Solid Tumor