GB7008-05 / Genechem - LARVOL DELTA

[VIRTUAL] CLDN6 and CLDN9 dual targeting antibody drug conjugates for the treatment of ovarian and endometrial cancers (AACR 2021) - "Both candidates demonstrated superior antibody-mediated antigen internalization than ASP1650, the forerunner in clinical trials. GB7008-03 and GB7008-05 also showed good ADCC potency on CLDN6 expressing tumor cell lines. Currently we are developing antibody-drug-conjugates based on these two antibodies. In vivo efficacy of these ADCs in CDX models will be presented."

Embryonal Tumor • Endometrial Cancer • Oncology • Ovarian Cancer • Ovarian Serous Adenocarcinoma • Solid Tumor • Testicular Cancer • CLDN6

Shanghai Genechem Co., Ltd. (Genechem) Announces appointment of Dr. Eric Rowinsky and Dr. Manuel Hidalgo to Scientific Advisory board, and abstract presentation at AACR 2021 on Claudin 6 Ab and K-Ras TCR-T (PRNewswire) - "Shanghai Genechem Co., Ltd...that it will present two abstracts at AACR 2021, on an antibody against Claudin 6, and a TCR-T therapy against K-Ras mutations."

Clinical data • Oncology