ordopidine (ACR 325) / Saniona - LARVOL DELTA

Efficacy and Safety of VMAT-2 Inhibitors and Dopamine Stabilizers for Huntington's Chorea: A Systematic Review, Meta-Analysis, and Trial Sequential Analysis. (PubMed, Med Sci (Basel)) - "VMAT-2 inhibitors may suggest potential improvements in motor symptoms in Huntington's disease, while current evidence does not demonstrate a significant benefit of dopamine stabilizers. The safety profiles of both treatments appear generally comparable to placebo. Further rigorous and long-term studies are required to better establish their efficacy and safety."

Clinical • Journal • Retrospective data • Review • Genetic Disorders • Huntington's Disease • Movement Disorders

NeuroSearch announces the company's annual Report 2011 (Neurosearch) - Together with Huntexil, seridopidine & ordopidine constitute a range of patent families which are important to NeuroSearch; Seridopidine has been evaluated in P1 clinical studies with satisfactory results; Ordopidine has finalised the active part of a P1b study & data are currently being analysed; In order to focus on the development of Huntexil, NeuroSearch has decided not to initiate P2 studies for seridopidine and ordopidine at this time

Product update • Parkinson's Disease • Schizophrenia