mesenchymal stem cell therapy (MSC) / Royan Stem Cell Tech - LARVOL DELTA

Targeted mesenchymal stem cell therapy equipped with a cell-tissue nanomatchmaker attenuates osteoarthritis progression. (PubMed, Sci Rep) - "We observed substantial improvements in both symptomatic and radiographic OA caused by C-TMN, which was independent of exogenous MSCs. This new approach could predict a promising future for OA management."

Journal • Immunology • Osteoarthritis • Pain • Rheumatology

Mesenchymal Stem Cell Therapy for Osteoarthritis: Practice and Possible Promises. (PubMed, Adv Exp Med Biol) - "Here, the brief scientific review of MSC role in the control of OA as well as the proposed mechanisms are discussed. We provide an insight into the last 10 years' studies conducted on preclinical and clinical OA treatment as well as future opportunities in OA management strategies employing MSCs."

Journal • Immune Modulation • Immunology • Inflammation • Osteoarthritis • Pain • Rheumatology

Mesenchymal Stem Cell Therapy for SARS-CoV-2-related Acute Respiratory Distress Syndrome (clinicaltrials.gov) - P2/3; N=60; Recruiting; Sponsor: Royan Institute

Clinical • New P2/3 trial • Acute Respiratory Distress Syndrome • Infectious Disease • Novel Coronavirus Disease • Pulmonary Disease • Respiratory Diseases