S-1117 / Seismic Therap - LARVOL DELTA

Integrative Transcriptomic and Metabolomic Analysis Reveals the Molecular Regulatory Mechanisms of Leaf Rust Resistance in Zanthoxylum armatum. (PubMed, Biology (Basel)) - "High-performance liquid chromatography (HPLC) confirmed elevated vitexin, rutin, and hydroxy-β-sanshool accumulation in R-YF, while transcriptome profiling revealed 1117 differentially expressed genes (DEGs)...This resulted in the effective accumulation of defense metabolites, representing a potential key mechanism for resistance. This study provides a basis for the dissection of molecular mechanisms, resistance gene mining, and molecular breeding in Z. armatum."

Journal

Examining Diagnostic Criteria for Atypical Anorexia Nervosa Post Metabolic Bariatric Surgery. (PubMed, Int J Eat Disord) - "While BMI and %TWL did not distinguish AAN from non-ED, "Fear of weight gain" and "Extreme weight control behaviors" may be a better indicator of these problems among patients 1 year-post-MBS."

Journal • Anorexia • Genetic Disorders • Obesity

Awareness–knowledge gap in rare lung diseases among medical students (ERS 2026) - " A cross-sectional survey of 1117 medical students evaluated awareness, knowledge sources and attitudes using structured questionnaires and descriptive analysis... Medical students in our national setting demonstrate awareness of rare lung diseases, but knowledge remains superficial. The findings suggest an educational gap rather than lack of interest. Strengthening structured curriculum content within our training system may improve understanding and future clinical readiness."

Idiopathic Pulmonary Fibrosis • Immunology • Pulmonary Disease • Rare Diseases • Respiratory Diseases

Dietary Laver Intake and Risk of Incident Abdominal Obesity Among Korean Adults: An 18-Year Prospective Cohort Study. (PubMed, Nutrients) - " During 18 years of follow-up, 1202 men (39.4%) and 1117 women (46.4%) developed abdominal obesity... Higher habitual laver intake was associated with a lower risk of incident abdominal obesity in Korean adults. Further prospective and intervention studies are needed to confirm these findings."

Journal • Cardiovascular • Diabetes • Genetic Disorders • Metabolic Disorders • Obesity • Type 2 Diabetes Mellitus

Vibration frequency drives oxidative membrane damage and metabolic remodeling underlying muscle quality deterioration in yellow catfish (Pelteobagrus fulvidraco) under waterless transport. (PubMed, Food Chem ) - "Untargeted metabolomics annotated 1117 metabolites and revealed frequency-dependent metabolic remodeling, with pronounced disturbances in glycerophospholipid metabolism and amino sugar and nucleotide sugar metabolism. Key membrane phospholipids and glycosyl donors were depleted under high-frequency vibration, suggesting impaired membrane stability and structural maintenance. Results demonstrate that transportation vibration stress impairs muscle quality via regulating energy metabolism, membrane lipid stability, glycosylation processes, and cell apoptosis, thus providing a theoretical basis to optimize aquaculture transport and improve the quality of flesh quality resilience during waterless transport."

Journal • Metabolic Disorders

Non-Invasive Assessment of Left Ventricular Myocardial Work in Conditions Associated With Increased Left Ventricular Wall Thickness. (PubMed, Echocardiography) - "Our study demonstrates distinct patterns of MW across conditions associated with increased LV wall thickness. These findings support the complementary role of MW assessment in the comprehensive evaluation of LV function and myocardial dysfunction. Larger prospective studies are required to establish its diagnostic and prognostic utility."

Journal • Amyloidosis • Cardiac Amyloidosis • Cardiovascular • Chronic Kidney Disease • Nephrology • Renal Disease

MoO3-x Incorporated Covalent Organic Framework Nanocomposite as an Advanced Anode Material for Li-Ion Batteries: Elucidating Structure-Activity Relationships. (PubMed, ACS Appl Mater Interfaces) - "MoO3 serves as a promising anode material for lithium-ion batteries (LIBs) because of its high theoretical capacity of 1117 mAh g-1 and its layered structure...Thus, this strategy of introducing transition metal oxides paves the way for regulating the valence, lattice structure, and even the composition of electrode materials through COF-based nanocomposite preparation. This approach equips these materials with desirable features and offers an alternative solution to meet the demands of energy storage systems."

Journal

State lines and species divides: Inconsistencies and opportunities in invasive species policies across the eastern United States. (PubMed, Ecol Appl) - "We found 1117 policy segments relevant to invasive species with 448 naming at least one taxon at the genus or species level...Policy inconsistency means that proactive states are susceptible to invasion from neighboring states where invasives are not similarly regulated. There is an opportunity to improve coordination between states to reduce vulnerability to invasives due to policy inconsistency."

Journal

Respiratory Versus Gastrointestinal Malignancies: Systemic Inflammation, Cardiovascular Burden, and All-Cause Mortality. (PubMed, J Clin Med) - "Mortality was higher in RSM than in GITM (42.3% vs. 29.9%), and SII was also higher in RSM (median 1117.8 vs. 716.8)...However, its added prognostic value was modest. SII should therefore be interpreted as a supportive inflammatory marker, together with tumor stage, metastatic disease, and the broader clinical condition of the patient."

Journal • Cardiovascular • Gastrointestinal Disorder • Oncology • Solid Tumor

Unstable housing conditions and PrEP use among younger and older transgender women in the U.S. (AIDS 2026) - "Characteristics, N (%) Overall N=4068 Not homeless 3796 (94.2) Sheltered homelessness 113 (2.8) Unsheltered homelessness N=121 (3.0) P 2 Age (%) Younger population (aged 15 to 24) Older population (aged 25+) 1595 (39.2) 2473 (60.8) 1487 (39.2) 2309 (60.8) 45 (39.8) 68 (60.2) 50 (41.3) 71 (58.7) 0.886 Education (%) College and above High school and below 2940 (72.5) 1117 (27.5) 2768 (73.1) 1018 (26.9) 74 (65.5) 39 (34.5) 75 (62.0) 46 (38.0) 0.006 Self-reported race/ethnicity (%) Black Hispanic Others White 103 (2.6) 146 (3.6) 714 (17.8) 3038 (75.9) 88 (2.4) 133 (3.6) 656 (17.6) 2859 (76.5) 5 (4.5) 6 (5.5) 27 (24.5) 72 (65.5) 6 (5.0) 6 (5.0) 25 (21.0) 82 (68.9) 0.042 Ever injected drugs(%) Experienced any type of gender identity stigma in family in the last 12 months (%) Experienced any type of gender identity stigma in healthcare settings in the last 12 months (%) Hormone use in the last 12 months 1 (%) With health insurance (%) 129 (3.2) 2126 (52.3) 2142 (52.7) 103 (2.5)..."

Clinical • Human Immunodeficiency Virus • Infectious Disease

Pulse pressure trajectories and diabetes risk: A gender-specific cohort study. (PubMed, Medicine (Baltimore)) - "Among 1117 (2.2%) incident diabetes cases during a median 1.69-year follow-up, elevated baseline PP was significantly associated with diabetes risk only in females (hazard ratio [HR] = 1.014, 95% confidence interval [CI]: 1.004-1.024)...Higher baseline PP and stable high PP trajectory show significant correlations with elevated diabetes risk among females, but not in males. These findings underscore the importance of gender-specific approaches in diabetes risk assessment and prevention."

Journal • Retrospective data • Diabetes • Metabolic Disorders

Fracture resistance and survival rates of chairside, milled, and 3D-printed provisional three-unit FDPs with two cements before and after masticatory simulation. (PubMed, Clin Oral Investig) - "This study informs clinicians on the fracture resistance of chairside, milled, and 3D-printed provisional FDPs with different cements, aiding material selection to improve durability and predictability of provisional restorations in clinical practice."

Journal • Musculoskeletal Diseases • Orthopedics

An intervention in search of an indication: A systematic review and meta-analysis of randomised trials of plasma transfusion (ISTH 2026) - "Populations in the included studies were cardiac surgery (13 trials, 1117 patients for mortality; 17 trials, 1403 patients blood loss), pre-hospital trauma (4 trials; 545 patients), in-hospital trauma (4 trials; 269 patients), DIC and sepsis (4 trials; 206 patients), neonates at risk of IVH (4 trials, 995 patients), renal impairment (1 trial; 63 patients) and liver disease (1 trial, 50 patients)...Chest tube drainage in trials in patients undergoing cardiac surgery (therapeutic use). Page 2 DOI*10.1016/j.rpth.2026.105713"

Retrospective data • Review • Cardiovascular • Hepatology • Infectious Disease • Renal Disease • Septic Shock

No Difference in Complications or Reoperation Rates Between Laminoplasty Versus Laminectomy and Fusion for Cervical Myelopathy in Patients With Parkinson's Disease. (PubMed, Clin Spine Surg) - "Complications and reoperation rates after laminectomy and fusion and laminoplasty in CSM patients with Parkinson disease were relatively low. Reoperation rates were similar between groups with a trend towards lower rates in laminoplasty, indicating that neurodegenerative disorders such as Parkinson disease do not always necessitate fusion."

Journal • CNS Disorders • Infectious Disease • Movement Disorders • Oncology • Osteoarthritis • Parkinson's Disease

Examination of the clinicopathological characteristics of HER2 ultra-low breast cancer (JBCS 2026) - "We added 1117 cases with low HER2 expression (1+ or 2+ and ISH negative) and compared clinicopathological factors and prognosis. Regarding prognosis, the HER2 ultra-low group showed a slightly better tendency compared to the HER2 null group, similar to previously reported findings. In the future, with the expansion of the indications for T-DXd, HER2 ultra-low breast cancer may become a clinically important subtype, and further investigation is needed."

Clinical • Breast Cancer • HER2 Breast Cancer • HER2 Positive Breast Cancer • Hormone Receptor Breast Cancer • Hormone Receptor Negative Breast Cancer • Hormone Receptor Positive Breast Cancer • Oncology • Solid Tumor • ER • HER-2

Incidence of Recurrent Otitis Media With Effusion (OME) Following Tympanostomy in Pediatric Patients: A Systematic Review and Cumulative Meta-Analysis. (PubMed, Int J Pediatr) - "From 1117 retrieved articles, 21 met the inclusion criteria...In addition, patients with cleft palate have a higher likelihood of OME recurrence and require long-term follow-up. These findings may assist physicians in refining treatment decisions based on individual patient characteristics and recurrence risk, though further high-quality clinical trials are needed to confirm these observations."

Journal • Retrospective data • Review • Infectious Disease • Otorhinolaryngology • Pediatrics

Financial Toxicity in 363 Breast Cancer Patients: Unique Challenges and Pan -Cancer Comparison (JBCS 2026) - "This study extracted data from 363 breast cancer patients from a questionnaire survey of 1117 cancer patients, comparing it with data from all cancer types to identify breast cancer-specific challenges that should be utilized in nursing practice...In the free-response section, there was a strong demand from healthcare professionals for the visualization of future total costs, i.e., the presentation of a "cost roadmap." The results of this survey suggest the importance of nurses collaborating with multidisciplinary healthcare professionals from the early stages of diagnosis to build comprehensive decision-making support that takes into account the patient's life plan. We believe that treating economic toxicity as a key aspect of care and promoting a multi-layered support system tailored to disease characteristics will contribute to improving the quality of breast cancer nursing."

Clinical • Breast Cancer • CNS Disorders • Mood Disorders • Oncology • Solid Tumor

Inspired by sponge predation mechanisms: preparation of hydrogel adsorbents based on carboxymethyl konjac glucomannan for rapid removal of basic fuchsin and methylene blue. (PubMed, Int J Biol Macromol) - "The adsorbent demonstrated rapid adsorption of basic fuchsin (BF) and methylene blue (MB), attaining adsorbed amounts of 1117.20 and 1245.60 mg·g-1 within 5 min, and maximum adsorption capacities of 1399.02 and 1524.71 mg·g-1, respectively. It also exhibited excellent anti-interference ability toward coexisting metal cations. Therefore, this biomimetic hydrogel offers a promising strategy for the efficient and rapid removal of cationic dyes from leather wastewater."

Journal

Neural correlates of emotion regulation associated with childhood trauma in major deprssive disorder (OHBM 2026) - "Results In the combined sample of participants with a lifetime diagnosis of MDD and healthy controls (Figure 1), the CT+ group reported higher cognitive reactivity ( U = 318, p < .001), greater depression severity ( U = 398, p < .001) , greater anxiety severity ( U = 414, p < .001), and lower positive mood following both positive task conditions (positive attend: U = 1125.5, p = .026; positive regulate: U = 1117, p = .032) compared with the CT− group...This may be due to the overlap between the two subgroups, as both have experienced deprivation, although the deprivation score is higher in the deprivation+threat group than in the deprivation-only group. In addition, the relatively small sample size in the subgroup analysis may have limited the statistical power and thus constrained the results."

Clinical • CNS Disorders • Depression • Major Depressive Disorder • Mental Retardation • Mood Disorders

Coordination Compensation Stabilization of Monodentate-Ligand Copper-Iodide Hybrids for Efficient Light-Emitting Diodes With Record-High External Quantum Efficiency Above 20. (PubMed, Adv Mater) - "Consequently, we fabricate LEDs reaching a record-high electroluminescence efficiency of 20.4% with an average of 19.8% over 60 devices, half-lifetime of 1117.5 h, large-area of 81 cm2, and demonstrate a broad universality applicable to various monodentate-ligand hybrids, representing a sufficiently striking advance over existing copper-iodide systems. The study provides a new strategy to pave the way for enhanced device performance of copper-iodide hybrid LEDs toward practical applications."

Journal

SYMPTOM BURDEN OF PATIENTS WITH MULTIPLE MYELOMA DURING THE LAST WEEK OF LIFE COMPARED TO OTHER HAEMATOLOGICAL MALIGNANCIES- A POPULATION-BASED REGISTRY STUDY (EHA 2026) - "n=4310 n=8974 n=6085 Sex Sex Male n, (%) 2357 (54.6%) 4703 (52.4%***¤) 3548 (58.3%***¤) Female n, (%) 1953 (45.3%) 4271 (47.5%) 2537 (41.6%) Age, median, IQR 78 (71-84) 82***¤ (75-88) 0-17 years 0 (0%) 28 (0.3%) 7 (0.1%) 18-64 years 500 (11.6%) 1190 (13.3%) 363 (6.0%) 65-74 years 1117 (25.9%) 2137 (23.8%) 1097 (18.0%) 75-84 years 1686 (39.1%) 3469 (38.7%) 2320 (38.1%) >85 years 1007 (23.4%) 2150 (24.0%) 2298 (37.8%) Pain n,(%) 3334 (77.4%) 6539***(72.9%) 4295***(70.6%) Nausea n,(%) 568 (13.2%) 1435***(16.0%) 836¤(13.7%) Breathlessness n,(%) 994 (23.1%) 2392***(26.7%) 1667***(27.4%) Anxiety n,(%) 2325 (53.9%) 4911 (54.7%) 3180*¤(52.3%) Confusion / Delirium n,(%) 1310 (30.4%) 2268***(25.3%) 1520***(25.0%) Death rattle n,(%) 2370 (55.0%) 3839***(42.8%) 2777***¤(45.6%)...Prevalence of symptoms in patients with Multiple Myeloma, aggressive and indolent haematological malignancies the last week in life. ***p<0.001, **p<0.01, *p<0.05"

Clinical • CNS Disorders • Hematological Malignancies • Mood Disorders • Multiple Myeloma

MATCHING-ADJUSTED INDIRECT COMPARISON (MAIC) OF PRIMARY EMPEGFILGRASTIM AND FILGRASTIM FN PROPHYLAXIS: FINAL RESULTS FROM EMPEREAL STUDY (MASCC-ISOO 2026) - "Results MONITOR-GCSF included 1117 patients...MAIC showed statistically significant superiority of empegfilgrastim over filgrastim in % of patients with FN (-5.0 (-6.3, -3.7) p<0.001), CIN4 (-9.8 (-14.4, -5.2) p<0.001), CIN3-4 (-16.9 (-22.1, -11.6) p<0.001), DLN (-8.7 (-10.8, -6.6) p<0.001). Conclusions Study have showed that empegfilgrastim is associated with a lower risk of FN and CIN in comparison with filgrastim in patients with solid tumors."

Clinical • Bladder Cancer • Breast Cancer • Chemotherapy-Induced Neutropenia • Febrile Neutropenia • Genito-urinary Cancer • Lung Cancer • Neutropenia • Ovarian Cancer • Prostate Cancer • Solid Tumor

The high-frequency magnitude (m3Hz) of Italian earthquakes from intensity data - the ICEM Catalog. (PubMed, Sci Data) - "We derive m3Hz for 1,951 earthquakes (from 1117 to 2020). The new earthquake catalog is defined by the acronym ICEM. For all earthquakes a quality index based on the variance-to-mean ratio (VMR) has been assigned."

Journal

LINC01117 promotes the malignant proliferation of lung adenocarcinoma by increasing HOXD8 mRNA stability. (PubMed, Mol Med Rep) - "The present study aimed to investigate the functional role and molecular mechanisms of long intergenic non‑protein coding RNA 1117 (LINC01117) in lung adenocarcinoma (LUAD)...Actinomycin D was used to inhibit RNA transcription...In conclusion, LINC01117 may serve as a notable prognostic biomarker that promotes cell proliferation in LUAD. HOXD8 may function as a downstream target of LINC01117, with LINC01117 exerting its pro‑proliferative effects by increasing HOXD8 mRNA stability."

Journal • Lung Adenocarcinoma • Lung Cancer • Non Small Cell Lung Cancer • Oncology • Solid Tumor • Squamous Cell Carcinoma • HOXD8

Smoking drives an epigenetic memory of aberrant hematopoiesis. (PubMed, medRxiv) - "12 DMPs collectively form the most long-lasting, persistent smoking-associated differentially methylated region (DMR) detected so far, spanning a 1117 bp region at ECEL1P1 . Smoking drives two distinct classes of DNAm alterations: transient, myeloid-specific changes and persistent, cell-type-shared signatures originating in HSPCs, forming a dual-track model of smoking-induced epigenetic remodeling."

Journal • Hematological Disorders • RUNX1