Vexol (rimexolone ophthalmic)
/ Novartis
- LARVOL DELTA
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October 20, 2022
Bioinformatics methods in biomarkers of preeclampsia and associated potential drug applications.
(PubMed, BMC Genomics)
- "In conclusion, the present study investigated key genes associated with PE pathogenesis that may contribute to identifying potential biomarkers, therapeutic agents and developing personalized treatment for PE."
Biomarker • Journal • Cardiovascular • Gynecology • Hypertension • Renal Disease
July 07, 2021
Comprehensive analysis of lncRNA-miRNA-mRNA regulatory networks for microbiota-mediated colorectal cancer associated with immune cell infiltration.
(PubMed, Bioengineered)
- "Three small molecule candidate anticancer drugs (Pentoxyverine, Rimexolone, and Doxylamine) were identified. A four-gene signature (FAM129A, BCL2, PMAIP1, and RPS6) is significantly correlated with immune infiltration level. This study provides a promising biomarker reservoir to explore the mechanism by which microbiota regulate the ceRNA network involving the immune response, and further participate in colorectal carcinogenesis and progression."
IO biomarker • Journal • Colorectal Cancer • Gastrointestinal Cancer • Oncology • Solid Tumor • BCL2 • HOTAIR • KCNQ1OT1 • LIFR • PMAIP1 • RPS6
September 23, 2020
[VIRTUAL] Candida albicans keratitis complicated with endophthalmitis after penetrating keratoplasty in Cogan’s syndrome
(ESCRS 2020)
- "She was treated with 10mg/ml rimexolone eye drops and systemic methotrexate...Systematic culture of corneoscleral rim may provide diagnostic orientation and may have prognostic implications, as prophylactic treatment could be initiated. We consider that frequent follow up should be conducted specially in immunosuppressed patients as the case reported."
Cataract • Keratitis • Ocular Infections • Ocular Inflammation • Ophthalmology
September 15, 2019
Long-term Outcomes on de novo Ocular Hypertensive Response to Topical Corticosteroids After Corneal Transplantation.
(PubMed, Cornea)
- "The use of alternate topical corticosteroids may be considered in cases of steroid-induced ocular hypertension after PKP because they offer good antiinflammatory prophylaxis with reduced hypertensive response."
Journal • Glaucoma • Graft versus Host Disease • Ocular Inflammation • Ophthalmology • Transplantation
April 23, 2020
Outcome and risk of ocular complications of managing children with chronic anterior uveitis with topical rimexolone 1.
(PubMed, Int Ophthalmol)
- "Rimexolone 1% ophthalmic suspension is an effective and safe topical steroid for pediatric anterior uveitis."
Clinical • Journal • Complement-mediated Rare Disorders • Glaucoma • Immunology • Ocular Inflammation • Ophthalmology • Pediatrics • Rare Diseases • Uveitis
February 19, 2020
"Echoworx Expands European Footprint With Nordic Language Support https://t.co/UaSveXOLgm"
(@NewsFromBW)
August 26, 2019
ACTIVATION OF NUCLEAR FACTOR ERYTHROID 2-RELATED (Nrf2) SYSTEM AS A NOVEL THERAPEUTIC APPROACH IN COPD
(ERS 2019)
- "Conclusions Bardoxolone, Omavexolone and Obacunone show a huge antioxidant response against CSE-induced COPD by Nrf2 activation. Thus, these drugs may represent a promising therapeutic option in COPD."
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