interferon alpha-2b topical (AP-001) / Helix BioPharma - LARVOL DELTA

Likelihood of polyhydroxyalkanoates production using canola oil cake and specific bacterial isolates for eco-friendly bioplastics. (PubMed, Biomater Sci) - "Chemical fingerprinting of the PHA film using Fourier transform infrared spectroscopy (FTIR) displayed unique functional groups - carbonyl (-CO-) and ester (-COO-) - at an explicit peak of 1718 cm-1, demonstrating that the polymer was polyhydroxybutyrate (PHB), for Bacillus cereus strain ST001 and Enterobacter cloacae strain AP001; however Rhodococcus ruber strain TESIII revealed a peak at 1653 cm-1 implying the existence of methylene (-CH-). It was further recorded that there was an increase in the intensity of 76.92% of tensile strength in PHA samples when bacteria were cultured in GRPD supplemented with the renewable carbon source. These findings explain the potential of canola oil cake as a cost-effective, renewable feedstock additive for enhancing PHA production and material quality, thus paving the way for future advancements in sustainable bioplastic development."

Journal

Enzyme-Linked Aptamer Assay (ELAA) for Detection of Toxoplasma ROP18 Protein in Human Serum. (PubMed, Front Cell Infect Microbiol) - "An Enzyme-Linked Aptamer Assay (ELAA) platform was developed using SELEX-derived aptamers, namely AP001 and AP002. A significant association between ELAA test positive for human serum samples and severe congenital toxoplasmosis was found (p = 0.006). Development and testing of aptamers-based assays opens a window for low-cost and rapid tests looking for biomarkers and improves our understanding about the role of ROP18 protein on the pathogenesis of human toxoplasmosis."

Journal • Preclinical