JNJ 49095397 / J&J - LARVOL DELTA

A utility of air-liquid interface cultured airway epithelium for the development of antiviral agents: translation beyond biology. (PubMed, Front Cell Infect Microbiol) - "Clinical experience with antiviral agents such as an RSV polymerase inhibitor (PC786) and a narrow-spectrum kinase inhibitor (RV568) further supports the translational utility of these systems. This review summarises the biological rationale for ALI airway models and highlights their expanding role in bridging mechanistic research with early clinical development."

Journal • Review • Infectious Disease • Respiratory Diseases • Respiratory Syncytial Virus Infections