morphine IR (PFR03318) / Ensysce Biosciences - LARVOL DELTA

Transcriptomic analysis of spinal microglia activation by opioids (Neuroscience 2017) - "Given that we also observed intact microglia activation following systemic morphine treatment in global MOR knockout mice, our results collectively suggest that morphine activates microglia through an opioid receptor-independent mechanism. We are now establishing the transcriptional signature of microglia activation following peripheral nerve injury or chronic opioid treatment to elucidate the mechanisms underlying microglial responses to particular insults."

Gold Standard • Addiction (Opioid and Alcohol) • Pain