Coronavirus Vaccine / Biken, National Institute of Biomedical Innovation, Osaka University - LARVOL DELTA

A multi-epitope pan-betacoronavirus vaccine construct predicted to induce broad-spectrum and durable immune responses: an immunoinformatics approach. (PubMed, Front Bioinform) - "This study identifies a promising in silico multi-epitope RBD-based pan-betacoronavirus vaccine candidate with predicted broad HLA population coverage and favorable structural stability. These findings provide a computational basis for subsequent experimental validation of the construct's immunogenicity, safety, and potential cross-protective capacity in relevant in vitro and in vivo models."

Journal • Infectious Disease • Novel Coronavirus Disease • Respiratory Diseases • IFNG • IL2

Hesitancy to receive the novel coronavirus vaccine and potential influences on vaccination among a cohort of healthcare workers in the Democratic Republic of the Congo. (PubMed, Vaccine) - "This study shows that, among a cohort of HCWs in the DRC who have likely been influenced by regional, national, and global factors, COVID-19 vaccine hesitancy has fluctuated during the pandemic and should not be treated as a static factor. Additional research to determine which factors most influence HCWs' willingness to receive the COVID-19 vaccine offers opportunities to reduce vaccine hesitancy among this important population through tailored public health messaging."

Journal • Infectious Disease • Novel Coronavirus Disease