TBI-1501
/ Jichi Medical University, Takara
- LARVOL DELTA
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June 22, 2022
Study of TBI-1501 for Relapsed or Refractory Acute Lymphoblastic Leukemia
(clinicaltrials.gov)
- P1/2 | N=21 | Active, not recruiting | Sponsor: Takara Bio Inc. | Recruiting ➔ Active, not recruiting
Enrollment closed • Acute Lymphocytic Leukemia • B Acute Lymphoblastic Leukemia • Hematological Malignancies • Leukemia • Oncology • CD19
June 14, 2017
Study of TBI-1501 for Relapsed or Refractory Acute Lymphoblastic Leukemia
(clinicaltrials.gov)
- P1/2; N=21; Recruiting; Sponsor: Takara Bio Inc.
Clinical • New P1/2 trial • Acute Lymphocytic Leukemia • B Acute Lymphoblastic Leukemia • CD19
December 28, 2020
Study of TBI-1501 for Relapsed or Refractory Acute Lymphoblastic Leukemia
(clinicaltrials.gov)
- P1/2; N=21; Recruiting; Sponsor: Takara Bio Inc.; Trial completion date: Mar 2020 ➔ Mar 2035; Trial primary completion date: Mar 2019 ➔ Mar 2035
Clinical • Trial completion date • Trial primary completion date • Acute Lymphocytic Leukemia • B Acute Lymphoblastic Leukemia • Hematological Malignancies • Leukemia • Oncology • CD19
June 14, 2017
Study of TBI-1501 for Relapsed or Refractory Acute Lymphoblastic Leukemia
(clinicaltrials.gov)
- P1/2; N=21; Recruiting; Sponsor: Takara Bio Inc.; Not yet recruiting ➔ Recruiting
Clinical • Enrollment open • Acute Lymphocytic Leukemia • B Acute Lymphoblastic Leukemia • CD19
December 03, 2016
"#ASH16 #bmtworkshop16 Carl June now discussing future or CART "need to learn lessons of Dendreon""
- @DrMiguelPerales
Clinical • Conference • Oncology
December 07, 2017
Cytokine Release Syndrome and Tumor Responses in a First-in-Man Trial of a Novel Affinity-Enhanced TCR-Gene Transduced T Cell Transfer Targeting NY-ESO-1 Antigen
(ASH 2017)
- "...In CD19-CAR-T cell therapy, high incidence of cytokine release syndrome (CRS) is associated with in vivo CAR-T cell proliferation and its clinical efficacy...They were managed the treatment of anti-IL-6 receptor monoclonal antibody, tocilizumab...In one patient, progression-free survival lasted more than 8 months. In summary, the affinity-enhanced NY-ESO-1 TCR-T cell transfer exhibited CRSs in association with in vivo cell proliferation and sequential tumor responses."
CAR T-Cell Therapy • Biosimilar • Hematological Malignancies • Oncology • Sarcoma • Solid Tumor
September 20, 2017
CD19 chimeric antigen receptor T cell therapy: Approval and launch in Japan for adult ALL in FY2021
(Takara)
- Annual Report 2017
Japanese regulatory • Launch Japan • Acute Lymphocytic Leukemia • Hematological Malignancies • Leukemia • Oncology
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