DS-1150b / Daiichi Sankyo - LARVOL DELTA

Discovery of DS-1150b, a novel xanthene compound for activating GLUT4 translocation. (PubMed, Bioorg Med Chem Lett) - "DS-1150b was found to promote GLUT4 translocation in L6-myotubes in rats and showed a glucose-lowering effect in an oral glucose tolerance test (oGTT) in a Zucker fatty rat model. Identification of naphthalene analog DS20060511 is also briefly described."

Journal • Diabetes • Metabolic Disorders • Type 2 Diabetes Mellitus • SLC2A4