DS-1150b
/ Daiichi Sankyo
- LARVOL DELTA
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March 24, 2025
Discovery of DS-1150b, a novel xanthene compound for activating GLUT4 translocation.
(PubMed, Bioorg Med Chem Lett)
- "DS-1150b was found to promote GLUT4 translocation in L6-myotubes in rats and showed a glucose-lowering effect in an oral glucose tolerance test (oGTT) in a Zucker fatty rat model. Identification of naphthalene analog DS20060511 is also briefly described."
Journal • Diabetes • Metabolic Disorders • Type 2 Diabetes Mellitus • SLC2A4
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