GQ1035
/ GeneQuantum Healthcare
- LARVOL DELTA
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March 18, 2026
GQ1035: First-in-class ADC against novel targets for gastric cancer and ovarian cancer discovered via high-throughput screening
(AACR 2026)
- "In this screen, TopoIi-ADC and Exatecan-ADC demonstrated superior anti-tumor activity compared to other payload-based ADCs (e.g., DXd, MMAE, Eribulin). GQ1035 shows a promising efficacy profile against gastric and ovarian cancers in preclinical PDO and PDX models. This positions GQ1035 as a potential breakthrough therapy in an area of high unmet medical need. It stands as a pioneering example of the strategic shift in biomedicine from "by design" to "by screening"."
ADC • Gastric Cancer • Oncology • Ovarian Cancer • Solid Tumor • CLDN18 • FOLR1
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