KB-001 / Keystone Bio - LARVOL DELTA

Further Preclinical Development of a Bio-therapeutic Against Porphyromonas gingivalis for the control of Systemic and Neuro-inflammation related Dementia and Alzheimer’s Disease (AAIC 2023) - "Keystone Bio has further developed both a companion diagnostic (CDx) and a clinical, proof-of-concept tested, first generation, safe, efficacious, precision, bio-therapeutic murine monoclonal antibody (KB-001) for the diagnosis, treatment and monitoring against the oral bacteria and major virulent factor/toxin of Pg...al 2021). The talk will review what now seems like a solid case for causation in the role of virulent/toxin secreting strains of in neuro-inflammation leading to cognitive decline, dementia, Sporadic Alzheimer’s disease and possibly Parkinson’s."

Preclinical • Alzheimer's Disease • Cardiovascular • CNS Disorders • Dementia • Diabetes • Inflammation • Metabolic Disorders • Movement Disorders • Parkinson's Disease • CD31 • PECAM1

PORPHYROMONAS GINGIVALIS OUTER MEMBRANE VESICLES AS THE MAJOR CAUSATIVE FACTOR OF NEURO-INFLAMMATION/DEGENERATION LEADING TO COGNITIVE DECLINE, DEMENTIA AND ALZHEIMER'S DISEASE (ADPD 2023) - "Results Keystone Bio has further developed both a companion diagnostic (CDx) and a clinical, proof-of-concept tested, first generation, safe, efficacious, precision, bio-therapeutic murine monoclonal antibody (KB-001) for the diagnosis, treatment and monitoring against the oral bacteria and major virulent factor/toxin of Pg...The talk will review what now seems like a solid case for causation in the role of virulent/toxin secreting strains of in neuro-inflammation leading to cognitive decline, dementia, Sporadic Alzheimer's disease and possibly Parkinson's. Conclusions The talk will review what now seems like a solid case for causation in the role of virulent/toxin secreting strains of in neuro-inflammation leading to cognitive decline, dementia, Sporadic Alzheimer's disease and possibly Parkinson's."

Alzheimer's Disease • Cardiovascular • CNS Disorders • Dementia • Diabetes • Immunology • Inflammation • Metabolic Disorders • Movement Disorders • Parkinson's Disease • CD31 • PECAM1