desonide cream/ointment/lotion / Generic mfg. - LARVOL DELTA

Topical B5 Repair Cream Combined with Desonide Cream Improves Lichen Simplex Chronicus Lesions via Inhibiting NGF: A Prospective, Self-Bilateral Controlled Trial (ChiCTR) - P=N/A | N=40 | Not yet recruiting | Sponsor: The Second Affiliated Hospital of Xi 'an Jiaotong University; The Second Affiliated Hospital of Xi 'an Jiaotong University

New trial • Dermatitis • Dermatology • Immunology

Efficacy and safety of MuShengshu in the treatment of mild-to-moderate atopic dermatitis: protocol for a randomized, double-blind, placebo-controlled trial. (PubMed, Front Med (Lausanne)) - "Meanwhile, the foundational therapies include desonide cream for mild AD and triamcinolone acetonide cream for moderate AD, both of which will be applied twice daily for 2 weeks. Findings in this study are expected to provide evidence for the incorporation of traditional Chinese herbal bath solutions into the comprehensive management of AD. https://www.chictr.org.cn/, Identifier ITMCTR2025001206."

Clinical • Journal • Atopic Dermatitis • Dermatitis • Dermatology • Immunology • Inflammation • Pruritus

Observation of the Efficacy of Rabbit Head Mom Multi-Effect Protective Essence Cream in the Adjuvant Treatment of Mild to Moderate Atopic Dermatitis in Children (ChiCTR) - P=N/A | N=100 | Completed | Sponsor: Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine; Shanghai Children's Medical Center, Shanghai Jiao Tong Universit

New trial • Atopic Dermatitis • Dermatitis • Dermatology • Immunology

Hydroxybutyl Chitosan Hydrogel Promotes Ablative Fractional CO2 Laser Wound Healing: A Prospective, Randomized, Split-Face Trial and Animal Model Evidence. (PubMed, Lasers Surg Med) - P=N/A | "HBC is effective and safe for promoting wound healing post AFCL. HBC upregulates IRF7 and Ctss expression and promotes macrophage M2 polarization. The expression of IRF7/CTSS may be correlated with M2 polarization of macrophages."

Journal • Preclinical • Acne Vulgaris • Dermatology • Pain • CTSS • EGF • IRF7

A Randomized Controlled Study of Oxysophocarpine Cream in the Treatment of Mild to Moderate Atopic Dermatitis (ChiCTR) - P=N/A | N=78 | Not yet recruiting | Sponsor: Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine; Yueyang Hospital of Inte

New trial • Atopic Dermatitis • Dermatitis • Dermatology • Immunology

A Comparative, Multicenter, Prospective, Randomized Study to Evaluate the Efficacy, Safety, and Delay of Relapse of Ceramide-Based Post-biotic Moisturizer Versus Paraffin-Based Moisturizer in Mild to Moderate Atopic Dermatitis. (PubMed, Cureus) - "Although both moisturizers were effective in resolving symptoms in the treatment phase, the ceramide-based post-biotic moisturizer was more effective and statistically significant in extending the remission period against the paraffin-based moisturizer in patients with mild to moderate AD."

Journal • Atopic Dermatitis • Dermatitis • Dermatology • Immunology • Inflammation

Study on the clinical efficacy of soothing moisturizing repairing cream combined with desonide in the treatment of atopic dermatitis in children. (PubMed, Medicine (Baltimore)) - "The combination of moisturizing cream and desonide in the treatment of AD in children is highly effective and safe. It is worth promoting for clinical application due to its significant therapeutic effects and high safety profile."

Clinical • Journal • Atopic Dermatitis • Dermatitis • Dermatology • Immunology

Different variants of Lichen Planus Pigmentosus in Filipino patients: A case series (EADV 2024) - "He began taking Delamanid and Linezolid for multidrug- resistant tuberculosis (MDR-TB) clinical trial in the same month, which then led to extensive hair loss...Patients received treatment with low-dose isotretinoin, topical tacrolimus 0.1%, desonide cream, and photoprotection... The cases show a wide range of etiologies and presentations of lichen planus pigmentosus in Filipino patients. While LPP can occur without a clear cause, potential etiologic agents such as hypopigmenting agents should be considered. Pediatric cases present additional challenges due to rarity and unidentified causes."

Clinical • Alopecia • Dermatitis • Dermatology • Dermatopathology • Human Immunodeficiency Virus • Immunology • Infectious Disease • Lichen Planus • Pediatrics • Pruritus • Respiratory Diseases • Tuberculosis

Randomized controlled study on the treatment of mild to moderate atopic dermatitis with licorice extract cream (ChiCTR) - P=N/A | N=72 | Recruiting | Sponsor: Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai; Yueyang Hospital of Integrated Traditional Chinese and Western Medi

New trial • Atopic Dermatitis • Dermatitis • Dermatology • Immunology

Efficacy and safety of LED-LLLT for treatment of patients with seborrheic dermatitis: a multicenter, single-blind, randomized, clinical Trial (ChiCTR) - P=N/A | N=80 | Not yet recruiting | Sponsor: Xiangya Hospital of Central South University; Xiangya Hospital Central South University

New trial • Dermatitis • Dermatology • Immunology • Seborrheic Dermatitis

Evaluation of bioequivalence and pharmacokinetic profiles for topical desonide cream using Chinese skin. (PubMed, Skin Pharmacol Physiol) - "This study demonstrated the applicability of skin blanching assay in Chinese skins and established the bioequivalence of test and reference desonide creams."

Journal • PK/PD data

Filament coating system assists recovery of ablative fCO laser treatment: A split-face clinical observation. (PubMed, J Cosmet Dermatol) - "Filament coating system was effective, safe, convenient, and economic in assisting recovery of ablative fCO laser, which might be a new option for additional nursing procedure."

Journal • Acne Vulgaris • Dermatology • Pain • HER-2

Beyond steroids and calcineurins; topical epigallocatechin-gallate and CBD shampoo alternatives for resistant alopecia areata totalis (WCD 2023) - "BACKGROUND: A 3-year-old female with no significant medical history presents with one year of alopecia areata totalis treated with several dermatologists with: multiple hair shampoos, topical minoxidil (5%), topical tacrolimus (0.3%), systemic (prednisolone), and topical steroids without improvement...We started treatment with CBD + nanoxidil shampoo daily (Revita-CBD, DS-laboratories), topical nanoxidil (Spectral DNC-L, DS laboratories) in the morning; occlusive desonide (Desowen, Galderma laboratories)by night 3 days a week and tacrolimus 0.3% (Traderma, Advaita laboratories) in the morning and the days without desonide, red light therapy (Kabel device, Sesderma laboratories) 3 days a week...Skin Appendage Disord. 2020 Nov;6(6):355-361"

Alopecia • Dermatology • CD8

"T -bact cream Cetaphil lotion + Desowen cream TESS buccal paste (Started by Dermatologist)" (,@oncologician)

Dermatology

Psoriasis Alba (White Psoriasis) of the Perianal Region. (PubMed, Skinmed) - "Based on pathologic features, a diagnosis of psoriasis alba was confirmed, and the patient was started on desonide lotion (0.05%) to be applied in the morning and tacrolimus cream (0.1%) at night, plus oral antihistamines. At the follow-up visit 3 weeks later, the lesions diminished to a great extent (Figure 3)."

Journal • Dermatology • Dermatopathology • Genetic Disorders • Human Immunodeficiency Virus • Immunology • Infectious Disease • Psoriasis

"True and effective! @MichaelKMaley @dr_amine_ovni @ProBiologist @RaviParikhMD @swathisomisetti @KovachEyeInsti @eyemikezein @GSchmuter @Desowenod @TrishaWerner1" (,@CathyEye)

[VIRTUAL] Linear morphea with evidence of hair regrowth (SID 2020) - "Minoxidil was initially trialed without resulting hair regrowth. The patient was subsequently treated with topical calcitriol, desonide cream and fluocinonide cream for one year. Thereafter, he exclusively used pimecrolimus cream twice daily with regrowth of hair noted on clinical and dermoscopic evaluation. Although linear morphea may result in scarring alopecia, our patient remarkably experienced hair regrowth throughout his treatment. Our report demonstrates the importance of dermoscopy in assisting diagnosis of linear morphea and highlights the utility of dermoscopy in monitoring progression or improvement of disease, as evidenced by the short vellus hairs on dermoscopy, as well as a tool to monitor progression or resolution of disease, as evidenced by short vellus hairs on dermoscopy."

Alopecia • Dermatopathology • Fibrosis • Immunology

The improvement of infantile atopic dermatitis during the maintenance period: a multicentre, randomised, parallel controlled clinical study of emollients in Prinsepia utilis Royle. (PubMed, Dermatol Ther) - "The application of emollients during the maintenance period of infantile AD can significantly reduce the risk of AD flares, prolong the time to flare and improve the clinical symptoms."

Clinical • Journal

A case of burn cicatrix with disseminated discoid lupus erythematosus (SID 2019) - "More interestingly, the lesions have seasonal and ultraviolet aggravated .With the help of pathological and immunological examination, the diagnosis were 1. Disseminated Dlupus Erythematosus (DDLE) 2.Hypertrophic Scar.With one month of treatment were given: hydroxychloroquine sulfate tablets 0.2g,bid ,po; nicotinamide tablets 200mg, tid po; desonide cream ad us,int , sun protection , the condition has improved including itches relieved, facial skin lesions subsided, and the skin color of the scalp, ears and limbs became lighter and the lesions became flat."

Clinical