XEN 103 / Xenon, Novartis - LARVOL DELTA

Mendelian randomization analysis to identify potential drug targets for osteoarthritis. (PubMed, PLoS One) - "Based on our comprehensive analysis, we can draw the conclusion that there is a causal relationship between the genetic levels of DNAJB12, USP8, IL12B, and RGMB and the risk of respective OA.They may be potential options for OA screening and prevention in clinical practice. They can also serve as candidate molecules for future mechanism exploration and drug target selection."

Journal • Immunology • Osteoarthritis • Pain • Rheumatology • IL12B • USP8