QA102 / MingMed Biotech - LARVOL DELTA

Oral QA102 Reduces Drusen Volume and Geographic Area Growth in Intermediate Atrophic Age-Related Macular Degeneration (ARVO 2026) - P2 | "The observed efficacy data suggest that QA102 may decrease the rate of growth of drusen volume and GA area and may slow disease progression in AMD. Larger clinical trials are warranted to confirm these Phase 2 results."

Age-related Macular Degeneration • Dry Age-related Macular Degeneration • Macular Degeneration • Ophthalmology • Retinal Disorders

AMEND: QA102 Phase II Study in Subjects With Dry AMD (clinicaltrials.gov) - P2 | N=150 | Completed | Sponsor: Smilebiotek Zhuhai Limited | Active, not recruiting ➔ Completed

Trial completion • Age-related Macular Degeneration • Dry Age-related Macular Degeneration • Macular Degeneration • Ophthalmology • Retinal Disorders

AMEND: QA102 Phase II Study in Subjects With Dry AMD (clinicaltrials.gov) - P2 | N=145 | Active, not recruiting | Sponsor: Smilebiotek Zhuhai Limited | Trial completion date: Oct 2025 ➔ Jan 2025 | Trial primary completion date: Oct 2025 ➔ Jan 2025

Trial completion date • Trial primary completion date • Age-related Macular Degeneration • Dry Age-related Macular Degeneration • Macular Degeneration • Ophthalmology • Retinal Disorders

AMEND: QA102 Phase II Study in Subjects With Dry AMD (clinicaltrials.gov) - P2 | N=145 | Active, not recruiting | Sponsor: Smilebiotek Zhuhai Limited | Recruiting ➔ Active, not recruiting | N=240 ➔ 145

Enrollment change • Enrollment closed • Age-related Macular Degeneration • Dry Age-related Macular Degeneration • Macular Degeneration • Ophthalmology • Retinal Disorders

AMEND: QA102 Phase II Study in Subjects With Dry AMD (clinicaltrials.gov) - P2 | N=240 | Recruiting | Sponsor: Smilebiotek Zhuhai Limited | Not yet recruiting ➔ Recruiting

Enrollment open • Age-related Macular Degeneration • Dry Age-related Macular Degeneration • Macular Degeneration • Ophthalmology • Retinal Disorders

AMEND: QA102 Phase II Study in Subjects With Dry AMD (clinicaltrials.gov) - P2 | N=240 | Not yet recruiting | Sponsor: Smilebiotek Zhuhai Limited

New P2 trial • Age-related Macular Degeneration • Dry Age-related Macular Degeneration • Macular Degeneration • Ophthalmology • Retinal Disorders