DopaMat (dopamine intranasal) / MetP Pharma - LARVOL DELTA

The mediating effect of maturity on anxiety and the motives for postponing parenthood. (PubMed, Sci Rep) - "The respondents completed the State-Trait Anxiety Inventory (STAI), the Maturity to Parenthood Scale (MPS), and the Multidimensional Scale of Motives for Postponing Parenthood (MSMPP-18)...In all six of the seven models (except "worry"), at least one of the factors of maturity to parenthood mediated the relationship between trait anxiety and motives for postponing parenthood/total score. Based on the results it can be assumed that a tendency to direct attention to a threat related to the context of child-bearing and child-rearing may lead to lower maturity to parenthood, which in turn may result in various motives for postponing parenthood."

Journal • Mood Disorders • Psychiatry

D-like receptor activation by intranasal dopamine attenuates fear responses induced by electrical stimulation of the dorsal periaqueductal grey matter, but fails to reduce aversion to pit vipers and T-maze performance. (PubMed, J Psychopharmacol) - "Wistar rats exposed to ES-dPAG were treated with Sulpiride (SUL, 40 mg/kg, D-like receptor antagonist) previously IN-DA (2 mg/kg)...These findings cannot be attributed to motor performance. The decision-making responses to avoid dangerous situations can be orchestrated by supra-mesencephalic structures connected by non-dopaminergic inputs."

Journal • CNS Disorders

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