NLS-11 / NLS Pharma - LARVOL DELTA

Effects of NLS-11 (Benedin) on Memory in the Novel Object Recognition Test in Mice (ASCP 2023) - "The results of this pre-clinical study suggest that NLS-11 induced a long term memory improvement which was significant and of the same extent to that induced by donepezil. At doses tested, NLS-11 did not reduce exploratory behavior, contrary to donepezil, suggesting that NLS-11 may induce less side effects than donepezil. Learning Objectives Describe the specific pharmacology of NLS-4 Describe the process by which NLS-4 is developed"

Preclinical • Alzheimer's Disease • CNS Disorders • Dementia

Nurse Led Sedation: The Clinical and Echocardiographic Outcomes of the 7-Year Emory Experience (TCT 2019) - "Background Our center has developed protocols for nurse-led sedation (NLS) in which nonanesthetist heart team nurses directly provide sedation with fentanyl and midazolam...Mean gradients were similar between groups (NLS 11.3 ± 46 mm Hg vs. MAC 11.8 ± 5.0 mm Hg; p = 0.47)...There are no clinically significant differences in post-deployment hemodynamic status or valve area with NLS compared with anesthetist-led moderate sedation. NLS is associated with significantly shorter procedure room time and contrast volume than anesthetist-led moderate sedation."

Clinical