RBM-006
/ RIBOMIC
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November 14, 2023
The Effect of Anti-Autotaxin Aptamers on the Development of Proliferative Vitreoretinopathy.
(PubMed, Int J Mol Sci)
- "Intravitreal administration of the anti-ATX aptamer also prevented tractional retinal detachment caused by PVR in the in vivo PVR model. We observed that the anti-ATX aptamer, RBM-006, inhibited PVR-related RPE cell proliferation and migration in vitro and inhibited the progression of PVR in the in vivo model, suggesting that the anti-ATX aptamer may be effective in preventing PVR."
Journal • Retinal Disorders
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