ICR62 / Roche - LARVOL DELTA

CTV-free lung planning: Can we reduce toxicity whilst maintaining local control? (ESTRO 2023) - "This contradicts the conventional ICRU62 recipe for target volumes but early clinical studies report no loss in local or marginal control and significantly lower rates of acute radiation pneumonitis...Although further validation of this methodology in larger patient cohorts is required, our findings are concordant with the results of clinical studies. Further study to better understand the risks and benefits of CTV-free treatment planning is warranted."

Lung Cancer • Non Small Cell Lung Cancer • Oncology • Pneumonia • Solid Tumor

[VIRTUAL] Stimulation for Bilateral Inferior Petrosal Sinus Sampling May Be Unnecessary for Diagnosis of ACTH Dependent Cushing Syndrome (ENDO-I 2020) - "Right basal ACTH was 465 pg./ml (ICR 62-1250), ACTH at 3 minutes was 647 (ICR 227-2610), ACTH at 5 minutes was 1250 (ICR 245-1965), ACTH at 10 minutes was 230 (71-550). Left basal ACTH was 230 (71-550), at 3 minutes was 453 (ICR 116-1250), at 5 minutes was 431 (91-1250), at 10 minutes was 534 (140-1250). Median basal ACTH ratio was 13.8 (ICR 5.1-26), at 3 minutes was 34.5 (ICR 13-82), at 5 minutes was 30.6 (11.4-49.8), at 10 minutes was 18.5 (8.2-48.2)."

Late-breaking abstract • Endocrine Disorders

Stimulation for Bilateral Inferior Petrosal Sinus Sampling May Be Unnecessary for Diagnosis of ACTH Dependent Cushing Syndrome. (ENDO 2020) - "Right basal ACTH was 465 pg./ml (ICR 62-1250), ACTH at 3 minutes was 647 (ICR 227-2610), ACTH at 5 minutes was 1250 (ICR 245-1965), ACTH at 10 minutes was 230 (71-550). Left basal ACTH was 230 (71-550), at 3 minutes was 453 (ICR 116-1250), at 5 minutes was 431 (91-1250), at 10 minutes was 534 (140-1250). Median basal ACTH ratio was 13.8 (ICR 5.1-26), at 3 minutes was 34.5 (ICR 13-82), at 5 minutes was 30.6 (11.4-49.8), at 10 minutes was 18.5 (8.2-48.2)."

Late-breaking abstract