Cellistem-OA (umbilical cord derived-mesenchymal stromal cells) / Cells for Cells - LARVOL DELTA

Efficacy of a single dose of cryopreserved human umbilical cord mesenchymal stromal cells for the treatment of knee osteoarthritis:a randomized, controlled, double-blind pilot study. (PubMed, Cytotherapy) - "This pilot study revealed that a single dose of CellistemOA is safe and superior to the active comparator in knee OA at 1-year of follow-up, making it a compelling therapeutic alternative to treat symptomatic OA patients."

Journal • Stroma • Immunology • Musculoskeletal Diseases • Osteoarthritis • Pain • Rheumatology

Intra-articular Injection of MSC-derived Exosomes in Knee Osteoarthritis (ExoOA-1) (clinicaltrials.gov) - P1; N=10; Not yet recruiting; Sponsor: Francisco Espinoza

Clinical • New P1 trial • Immunology • Osteoarthritis • Pain • Rheumatology

Cell Therapy With Cellistem-OA for Symptomatic Knee Osteoarthritis (clinicaltrials.gov) - P1/2; N=30; Not yet recruiting; Sponsor: Fundación Oftalmológica de Santander Clínica Carlos Ardila Lulle

Clinical • New P1/2 trial • Immunology • Osteoarthritis • Pain • Rheumatology

The most effective Chilean cell therapy worldwide in reducing pain in knee osteoarthritis [Google Translation] (El Mostrador) - "To date, more than 350 patients have already been treated in different health centers in the country. Internationally, the treatment is being used in Peru and its prompt commercialization is expected in Colombia and other markets such as the United States and Brazil."

Launch non-US