Follistim AQ Cartridge (follitropin beta) / Organon - LARVOL DELTA

HEART: Hormone Evaluation in Artificial Reproductive Technology (clinicaltrials.gov) - P=N/A | N=810 | Completed | Sponsor: Lund University | Phase classification: P4 ➔ P=N/A | Trial completion date: Jun 2024 ➔ Oct 2024

Phase classification • Trial completion date • Gynecology • Infertility • Sexual Disorders

Follitropin Alpha versus Follitropin Beta in IVF/ICSI Cycle: A Retrospective Cohort Study. (PubMed, Drug Des Devel Ther) - "Furthermore, Puregon can eliminate unneeded anxiety and expenses while also administering more flexibility. Taken together, these findings could well be utilized in everyday clinical practice to better inform patients when deciding on an ovarian stimulation strategy."

Clinical • Journal • Retrospective data • Gynecology • Infertility • Mood Disorders • Psychiatry

Impact of FSH Dosage During Ovarian Stimulation for IVF/ICSI in Granulosa Cells (clinicaltrials.gov) - P1 | N=6 | Completed | Sponsor: ART Fertility Clinics LLC | Recruiting ➔ Completed | N=10 ➔ 6 | Trial completion date: Jan 2024 ➔ Jun 2024 | Trial primary completion date: Dec 2023 ➔ Mar 2024

Enrollment change • Trial completion • Trial completion date • Trial primary completion date • Gynecology • Infertility • Sexual Disorders

HEART: Hormone Evaluation in Artificial Reproductive Technology (clinicaltrials.gov) - P4 | N=796 | Completed | Sponsor: Lund University | Trial completion date: Dec 2020 ➔ May 2024

Adverse events • Biomarker • Trial completion date • Gynecology • Infertility • Sexual Disorders

PPOS (Progestin Primed Ovarian Stimulation) and Corifollitropin Alfa (CFA) Cross-over Study (clinicaltrials.gov) - P4 | N=60 | Not yet recruiting | Sponsor: University Hospital, Ghent | Initiation date: Apr 2024 ➔ Jul 2024

Trial initiation date

Comparison of DNA damage in granulosa cells of women undergoing controlled ovarian stimulation in in vitro fertilization protocols with the recombinant human follicle-stimulating hormones Corneumon®, Gonal-F®, Pergoveris® and Puregon®: a randomized trial. (PubMed, Arch Gynecol Obstet) - "Use of Corneumon® and Pergoveris® in COS caused statistically significantly lower levels of DNA damage in GCs of infertile women undergoing ART, which could potentially correlate with better reproductive outcomes."

Journal • Preclinical • Gynecology • Infertility • Sexual Disorders

PPOS (Progestin Primed Ovarian Stimulation) and Corifollitropin Alfa (CFA) Cross-over Study (clinicaltrials.gov) - P4 | N=60 | Not yet recruiting | Sponsor: University Hospital, Ghent | Initiation date: Jan 2024 ➔ Apr 2024

Trial initiation date

TROPIX: Usefulness of Corifollitropin α as Alternative to Conventional Daily rFSH Protocols in Oocyte Donors Undergoing Pituitary Suppression With Medroxiprogesterona Acetate (MPA) (clinicaltrials.gov) - P=N/A | N=318 | Not yet recruiting | Sponsor: Instituto Valenciano de Infertilidad, IVI VALENCIA

New trial • Infertility • Sexual Disorders

PPOS (Progestin Primed Ovarian Stimulation) and Corifollitropin Alfa (CFA) Cross-over Study (clinicaltrials.gov) - P4 | N=60 | Not yet recruiting | Sponsor: University Hospital, Ghent

New P4 trial

2-Shot: Comparison of Sequential CFA vs CFA +rFSH for Elective Fertility Preservation. (clinicaltrials.gov) - P3 | N=194 | Recruiting | Sponsor: Fundación Santiago Dexeus Font | Not yet recruiting ➔ Recruiting

Enrollment open • Trial completion date • Trial primary completion date

ELONVA FLARE PROTOCOL: a new approach for poor responders in superovulation for In Vitro Fertilisation (IVF). (ANZCTR) - P1 | N=20 | Completed | Sponsor: UNSW | Not yet recruiting ➔ Completed

Trial completion • Gynecology • Infertility • Sexual Disorders

Impact of FSH Dosage During Ovarian Stimulation for IVF/ICSI in Granulosa Cells (clinicaltrials.gov) - P1 | N=10 | Recruiting | Sponsor: ART Fertility Clinics LLC | Not yet recruiting ➔ Recruiting | Trial completion date: Aug 2023 ➔ Jan 2024 | Trial primary completion date: Jul 2023 ➔ Dec 2023

Enrollment open • Trial completion date • Trial primary completion date • Gynecology • Infertility • Sexual Disorders

Effect of Different Ovarian Stimulation Protocols on Endometrial Receptivity (clinicaltrials.gov) - P4 | N=24 | Completed | Sponsor: Instituto Valenciano de Infertilidade de Lisboa | Active, not recruiting ➔ Completed

Trial completion • Gynecology • Infertility • Sexual Disorders

Tailored Ovarian Stimulation Based on BMI, AMH, AFC (clinicaltrials.gov) - P4 | N=300 | Recruiting | Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain | Trial completion date: Jun 2021 ➔ Dec 2023 | Trial primary completion date: Jun 2021 ➔ Dec 2023

Trial completion date • Trial primary completion date • Infertility • Sexual Disorders

Effect of Different Ovarian Stimulation Protocols on Endometrial Receptivity (clinicaltrials.gov) - P4 | N=24 | Active, not recruiting | Sponsor: Instituto Valenciano de Infertilidade de Lisboa | Recruiting ➔ Active, not recruiting | Trial completion date: Dec 2022 ➔ May 2023 | Trial primary completion date: Dec 2022 ➔ May 2023

Enrollment closed • Trial completion date • Trial primary completion date • Gynecology • Infertility • Sexual Disorders

Impact of FSH Dosage During Ovarian Stimulation for IVF/ICSI in Granulosa Cells (clinicaltrials.gov) - P1 | N=10 | Not yet recruiting | Sponsor: ART Fertility Clinics LLC | Trial completion date: Nov 2022 ➔ Aug 2023 | Initiation date: Aug 2022 ➔ Mar 2023 | Trial primary completion date: Oct 2022 ➔ Jul 2023

Trial completion date • Trial initiation date • Trial primary completion date • Gynecology • Infertility • Sexual Disorders

Impact of FSH Dosage During Ovarian Stimulation for IVF/ICSI in Granulosa Cells (clinicaltrials.gov) - P1 | N=10 | Not yet recruiting | Sponsor: ART Fertility Clinics LLC | Initiation date: May 2022 ➔ Aug 2022

Trial initiation date • Gynecology • Infertility • Sexual Disorders

HEART: Hormone Evaluation in Artificial Reproductive Technology (clinicaltrials.gov) - P4 | N=796 | Completed | Sponsor: Lund University | Recruiting ➔ Completed

Adverse events • Biomarker • Trial completion • Gynecology • Infertility • Sexual Disorders

Impact of FSH Dosage During Ovarian Stimulation for IVF/ICSI in Granulosa Cells (clinicaltrials.gov) - P1 | N=10 | Not yet recruiting | Sponsor: ART Fertility Clinics LLC

New P1 trial • Gynecology • Infertility • Sexual Disorders

Effect of Different Ovarian Stimulation Protocols on Endometrial Receptivity (clinicaltrials.gov) - P4 | N=30 | Recruiting | Sponsor: Instituto Valenciano de Infertilidade de Lisboa | Trial completion date: Dec 2021 ➔ Dec 2022 | Trial primary completion date: Dec 2021 ➔ Dec 2022

Preclinical • Trial completion date • Trial primary completion date • Gynecology • Infertility • Sexual Disorders