isotretinoin / Generic mfg. - LARVOL DELTA

The effect of topical insulin in the treatment of isotretinoin-associated dry eye disease in patients with acne vulgaris. (PubMed, Int Ophthalmol) - "TI may represent a potentially useful therapeutic option for isotretinoin-associated dry eye disease."

Journal • Retrospective data • Acne Vulgaris • Dermatology • Dry Eye Disease • Ophthalmology

Best Practices for Managing Pseudofolliculitis Barbae: An Expert Consensus Delphi Study. (PubMed, JAMA Dermatol) - "No agreement was reached regarding a standardized grading scale, the use of oral isotretinoin for refractory disease, superficial chemical peels, or the use of multiblade razors. Using a Delphi consensus study approach, expert consensus guidelines were established for diagnosing and managing PFB. These recommendations provide an evidence-informed framework to support clinical decision-making, guide future research efforts, and help inform policy considerations associated with PFB management."

Journal • Aesthetic Medicine • Inflammation

FACEMICRO: Facial Skin Microbiome in Patients With Moderate-to-Severe Acne Vulgaris Treated With Isotretinoin (clinicaltrials.gov) - P=N/A | N=90 | Recruiting | Sponsor: Can Tho University of Medicine and Pharmacy

New trial • Acne Vulgaris • Dermatology

Physician Understanding and Perceptions of Risk Communication Related to Drugs Covered by Risk Evaluation and Mitigation Strategy Programs. (PubMed, Pharmacoepidemiol Drug Saf) - "While physicians largely expressed awareness of REMS testing requirements and found REMS programs to be valuable sources of risk communication, they would like more information on managing side effects, more accessible information on REMS requirements, integration of REMS programs with EMRs, and timely updates to REMS materials as new safety information emerges."

Journal

What's new in the treatment of scars (EADV 2026) - "*Other Treatments: Treatments for acne scars include topical retinoids, oral isotretinoin with fractional ablative CO2 laser, botulinum toxin A for surgical scars, and emerging therapies like dupilumab for keloids. Various treatments, including imiquimod cream, radiation therapy, laser treatment, and others, have been shown to reduce keloid recurrence rates and improve scar appearance. Genetic differences between keloids and other scar types suggest targeted therapeutic approaches could be beneficial.Objectives:1. To appreciate differences between keloids and other scars.2."

Acne Vulgaris • Aesthetic Medicine • Fibrosis

Prospective Exploratory Evaluation of Audiovestibular Function in Patients Receiving Oral Isotretinoin Using Audiometry and Videonystagmography. (PubMed, Turk Arch Otorhinolaryngol) - "Selected VNG-based vestibular assessments, including spontaneous nystagmus, gaze, positional, and oculomotor testing, remained within normal limits throughout the study period. Within the limitations of this exploratory pilot study, short-term oral isotretinoin therapy did not demonstrate clinically significant abnormalities in audiometric measurements or selected VNG-based vestibular assessments."

Journal • Acne Vulgaris • Dermatology • Ophthalmology

Ethical Considerations of Mandated iPLEDGE Pregnancy Testing. (PubMed, J Am Acad Dermatol) - No abstract available

Journal • Dermatology

An Unusual Presentation of Unilateral Rosacea Mimicking Majocchi's Granuloma Successfully Treated with Isotretinoin (EADV 2026) - No abstract available

Dermatology • Rosacea

Acitretin versus Isotretinoin in Pustular Psoriasis: A Real-World Comparative Study (EADV 2026) - No abstract available

Clinical • Real-world • Real-world evidence • Dermatology • Immunology • Psoriasis • Pustular Psoriasis

Oral Isotretinoin as a Potent Adjuvant to Azole Antifungals in Recalcitrant Dermatophytosis: A Case Series of 7 Patients (EADV 2026) - No abstract available

Clinical • Dermatology

Clinical Application of a Biomimetic Barrier-Repairing Lip Balm in Patients with Isotretinoin-Induced Cheilitis: A Case Series (EADV 2026) - No abstract available

Clinical

Off-label isotretinoin in refractory steatocystoma multiplex: sustained disease control and reduced procedural burden (EADV 2026) - No abstract available

Use of Oral Isotretinoin in the Management of Lichen Amyloidosis: A Case Report (EADV 2026) - No abstract available

Case report • Clinical • Amyloidosis

Beyond Standard Lipid Panels: Elevated Lipoprotein(a) in Young Adults with Prior Isotretinoin Exposure (EADV 2026) - No abstract available

Clinical

Combination of low-dose isotretinoin and 1450 nm non-ablative laser in moderate acne: a synergistic approach with reduced systemic burden (EADV 2026) - No abstract available

Acne Vulgaris

Concomitant Therapy of Oral Isotretinoin with Multiplex Pulsed Dye Laser and Nd: YAG Laser for Acne. (EADV 2026) - No abstract available

Acne Vulgaris

Treatment Success and Clinical Improvement Outcomes with Low-Dose Micronized Isotretinoin in Severe Recalcitrant Nodular Facial Acne: A Post Hoc Analysis of a Real-World Retrospective Electronic Medical Record-based Study (EADV 2026) - No abstract available

Real-world • Real-world evidence • Retrospective data • Acne Vulgaris

Assessing maternofetal risk associated with isotretinoin use preceding pregnancy: A retrospective cohort study (EADV 2026) - No abstract available

Retrospective data • Acne Vulgaris • Dermatology • Dermatopathology • Hidradenitis Suppurativa • Immunology

Evolution of olfactory function and associated factors in acne patients receiving oral isotretinoin: a longitudinal study (EADV 2026) - No abstract available

Clinical • Longitudinal study • Observational data • Acne Vulgaris

Effects of oral omega-3 fatty acids on isotretinoin tolerability in acne vulgaris: A systematic review and meta-analysis (EADV 2026) - No abstract available

Retrospective data • Review • Acne Vulgaris • Dermatology

Oral isotretinoin plus desloratadine for acne vulgaris: an updated global meta-analysis of efficacy, safety, and patient-centered outcomes (EADV 2026) - No abstract available

Retrospective data • Acne Vulgaris • Dermatology

Optimizing Isotretinoin Prescribing Safety: An AI-Driven Acne Assessment Model Integrating Lesion Staging with Atopic Dermatitis Risk Stratification (EADV 2026) - No abstract available

Clinical • Acne Vulgaris • Atopic Dermatitis • Dermatitis • Dermatology • Immunology

Platform and positive sentiment are associated with higher engagement per view in isotretinoin-related videos: a cross-sectional analysis (EADV 2026) - No abstract available

Acne Vulgaris • Dermatology • Dermatopathology • Hidradenitis Suppurativa • Immunology

Cumulative isotretinoin dosing (120 vs 150 mg/kg) and 12-month relapse in acne vulgaris: a randomized controlled trial (EADV 2026) - No abstract available

Clinical • Acne Vulgaris • Dermatology

Effectiveness and Tolerability of Low-Dose Micronized Isotretinoin in Severe Recalcitrant Nodular Facial Acne: A Severity-Stratified Analysis of a Real-World Retrospective Electronic Medical Record-based Study (EADV 2026) - No abstract available

Real-world • Real-world evidence • Retrospective data • Acne Vulgaris