fluticasone propionate / Generic mfg. - LARVOL DELTA

Diagnosis and treatment of a patient with severe hepatitis and rash caused by toripalimab: A case report. (PubMed, Medicine (Baltimore)) - "This case proposes that clinician should comprehensively determine the risk of adverse reactions and strengthen medication monitoring to ensure patient safety."

Journal • Hepatology • Inflammation • Liver Failure • Nasopharyngeal Carcinoma • Oncology • Solid Tumor

Seal, Stopping Eczema and Allergy Study (clinicaltrials.gov) - P2 | N=398 | Active, not recruiting | Sponsor: Kari Nadeau, MD, PhD | Recruiting ➔ Active, not recruiting

Enrollment closed • Allergy • Atopic Dermatitis • Dermatitis • Dermatology • Immunology

Seal, Stopping Eczema and Allergy Study (clinicaltrials.gov) - P2 | N=312 | Recruiting | Sponsor: Kari Nadeau, MD, PhD | Trial completion date: Jun 2027 ➔ Jun 2028 | Trial primary completion date: May 2027 ➔ May 2028

Trial completion date • Trial primary completion date • Allergy • Atopic Dermatitis • Dermatitis • Dermatology • Immunology

Q1 and Q2 Selection, Q3, IVRT, IVPT, pharmacokinetic and pharmacodynamic evaluation fo Topical Generic Product. (PubMed, Drug Dev Ind Pharm) - "A crucial study has exhibited that reference and test formulations are bioequivalent with a 90% confidence interval and results in 84.67%∼101.09%. The Cutivate® cream 0.05%, and proposed generic product Fluticasone Propionate cream 0.05% formulations are bioequivalent and have a favorable safety profile."

Journal • PK/PD data

Two Cases of Acquired Reactive Perforating Collagenosis in Hemodialysis Patients. (PubMed, Semin Dial) - "Two patients were treated with oral thalidomide and ebastine, local application of fluticasone propionate cream, and enhanced dialysis. We report for the first time that ARPC in patients with hemodialysis could be improved by oral thalidomide and antihistamines and local application of steroid. This report provides reference for guiding the understanding of ARPC and the new treatment of ARPC in hemodialysis patients."

Journal • Cardiovascular • Chronic Kidney Disease • Dermatology • Diabetes • Endocrine Disorders • Hypertension • Metabolic Disorders • Renal Disease • Type 2 Diabetes Mellitus

Comparative study on pharmacokinetics of fluticasone propionate cream in humans (ChiCTR) - P1 | N=12 | Not yet recruiting | Sponsor: Huzhou Central Hospital; Zhejiang Xianju Pharmaceutical Co., Ltd.

New P1 trial • Atopic Dermatitis • Dermatitis • Dermatology • Immunology

Seal, Stopping Eczema and Allergy Study (clinicaltrials.gov) - P2 | N=312 | Recruiting | Sponsor: Kari Nadeau, MD, PhD | Phase classification: P3 ➔ P2 | N=750 ➔ 312

Enrollment change • Phase classification • Allergy • Atopic Dermatitis • Dermatitis • Dermatology • Immunology

Seal, Stopping Eczema and Allergy Study (clinicaltrials.gov) - P3 | N=750 | Recruiting | Sponsor: Kari Nadeau | Phase classification: P2 ➔ P3 | Trial primary completion date: Jul 2026 ➔ May 2027

Phase classification • Trial primary completion date • Allergy • Atopic Dermatitis • Dermatitis • Dermatology • Immunology

Seal, Stopping Eczema and Allergy Study (clinicaltrials.gov) - P2; N=875; Recruiting; Sponsor: Kari Christine Nadeau, MD, PhD; Not yet recruiting ➔ Recruiting

Enrollment open • Allergy • Atopic Dermatitis • Dermatitis • Dermatology • Immunology

Seal, Stopping Eczema and Allergy Study (clinicaltrials.gov) - P2; N=875; Not yet recruiting; Sponsor: Kari Christine Nadeau, MD, PhD; Phase classification: P1/2 ➔ P2

Phase classification • Allergy • Atopic Dermatitis • Dermatitis • Dermatology • Immunology

Fluticasone propionate-loaded solid lipid nanoparticles with augmented anti-inflammatory activity: Optimization, characterization and pharmacodynamic evaluation on rats. (PubMed, J Microencapsul) - "The optimized FP-loaded SLNs maximized the efficacy of FP toward inflammation alleviation that increase its potential as efficient implement in inflammatory skin diseases remediation."

Journal • PK/PD data • Dermatology • Immunology • Inflammation • TNFA

Drugs for atopic dermatitis. (PubMed, Med Lett Drugs Ther) - No abstract available

Journal • Atopic Dermatitis • Dermatitis • Dermatology • Immunology