long-acting erythropoietin (HM10760A) / Hanmi - LARVOL DELTA

Single-and repeat-dose toxicity of HM10760A, a long-acting erythropoietin, in rats and monkeys. (PubMed, Toxicol Appl Pharmacol) - "Almost all observations recorded at the low- and mid-dose levels are typical pharmacological effects of EPO and not uniquely attributed HM10760A toxicity. To account for the differences between human being and animal physiologies, the safety of HM10760A needs to be further confirmed in future clinical studies."

Journal • Preclinical • Chronic Kidney Disease • Gene Therapies • Hematological Disorders • Nephrology • Renal Disease • EPO