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October 25, 2023
Opportunities for Cellular Rejuvenation in Alzheimer's Disease: How Epigenetic Reprogramming and Chaperone-Mediated Autophagy Are Enabling Next Generation Therapeutic Approaches.
(PubMed, J Prev Alzheimers Dis)
- "The protein buildups lead to aggregates that preclude proteostasis leading to cell toxicity. Small-molecule CMA activators restore proteostasis and limit toxicity enabling cellular rejuvenation."
Journal • Alzheimer's Disease • CNS Disorders • Gene Therapies
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