Epic (tetracaine spray) / Futura Medical - LARVOL DELTA

[VIRTUAL] Pulmonary Blood Flow Assessed by 15O-Water PET in Healthy Subjects and Patients with Pulmonary Hypertension (ATS-I 2020) - "Methods : 15O-water PET(500 MBq, dynamic scan for 6 minutes) was performed at rest and after exercise of ergometer at anaerobic metabolism threshold for 5 minutes in supine position...C onclusions : This preliminary study suggested that time to peak of 15O-water was significantly longer and more heterogeneous in the lungs in patients with CTEPH, compared with healthy subjects. 15O-H2O PET might be of potential use for the early detection of altered blood flow in the lung and repeatable evaluation of therapeutic intervention in pulmonary vascular diseases."

Clinical • Hypertension • Pulmonary Arterial Hypertension

Pulmonary Blood Flow Assessed by 15O-Water PET in Healthy Subjects and Patients with Pulmonary Hypertension (ATS 2020) - "Thus, quantitative assessment of pulmonary blood flow by 15O-water positron emission tomography(PET) may improve the diagnostic precision and the management of pulmonary vascular diseases.Objectives: We aimed to evaluate time to peak of 15O-H2O, at rest and after exercise assessed by PET between healthy subjects and patients with pulmonary hypertension. 15O-water PET(500 MBq, dynamic scan for 6 minutes) was performed at rest and after exercise of ergometer at anaerobic metabolism threshold for 5 minutes in supine position... This preliminary study suggested that time to peak of 15O-water was significantly longer and more heterogeneous in the lungs in patients with CTEPH, compared with healthy subjects. 15O-H2O PET might be of potential use for the early detection of altered blood flow in the lung and repeatable evaluation of therapeutic intervention in pulmonary vascular diseases."

Clinical

FM48: Study to Determine the Effect of a Newly Formulated Tetracaine Product PET500 on Penile Skin Sensation (clinicaltrials.gov) - P1; N=20; Completed; Sponsor: Futura Medical Developments Ltd.

New P1 trial