OG253 / Oragenics, Precigen - LARVOL DELTA

Preclinical evaluation of the maximum tolerated dose and toxicokinetics of enteric-coated lantibiotic OG253 capsules. (PubMed, Toxicol Appl Pharmacol) - "The well tolerated high dose of OG253 (425.7 mg/kg/day) is recommended as the MTD for safety and efficacy studies. Further preclinical study is needed to evaluate the safety profile of OG253 under longer exposure."

Journal • Preclinical • Immunology