FORTESTA (testosterone) / Endo - LARVOL DELTA

A Study of the Effect of Testosterone Replacement Therapy on Blood Pressure in Adult Male Participants With Hypogonadism (clinicaltrials.gov) - P4 | N=676 | Completed | Sponsor: Endo Pharmaceuticals | Active, not recruiting ➔ Completed

Trial completion • Endocrine Disorders

A Study of the Effect of Testosterone Replacement Therapy on Blood Pressure in Adult Male Participants With Hypogonadism (clinicaltrials.gov) - P4 | N=618 | Active, not recruiting | Sponsor: Endo Pharmaceuticals | Recruiting ➔ Active, not recruiting

Enrollment closed • Endocrine Disorders

A Study of the Effect of Testosterone Replacement Therapy on Blood Pressure in Adult Male Participants With Hypogonadism (clinicaltrials.gov) - P4 | N=618 | Recruiting | Sponsor: Endo Pharmaceuticals | Trial completion date: Dec 2022 ➔ Jul 2023 | Trial primary completion date: Dec 2022 ➔ Jul 2023

Trial completion date • Trial primary completion date • Endocrine Disorders

A Study of the Effect of Testosterone Replacement Therapy on Blood Pressure in Adult Male Participants With Hypogonadism (clinicaltrials.gov) - P4; N=729; Recruiting; Sponsor: Endo Pharmaceuticals; Trial completion date: Apr 2022 ➔ Dec 2022; Trial primary completion date: Apr 2022 ➔ Dec 2022

Clinical • Trial completion date • Trial primary completion date • Endocrine Disorders

[VIRTUAL] Trends in Testosterone Prescriptions Amongst Medical Specialties: A 5-year CMS Data Analysis (AUA 2021) - "TRT modalities were consolidated into four categories: Topical (Androderm, Androgel, Axiron, Fortesta, Natesto, Testim), oral (Android, Methitest, Methyltestosterone, Testred, Striant), injection (Aveed, Depo-Testosterone, Testosterone Cypionate, Testosterone Enanthate) and pellet (Testopel)... Although multiple TRT modalities exist, topical and injected are by far the most prescribed amongst this cohort. Topical therapy costs more than injection despite being prescribed less often. The wide variation in modalities of testosterone prescriptions illustrates an opportunity for treatment guidelines to be streamlined across all specialties in order to improve outcomes for all patients."

Urology

A Study of the Effect of Testosterone Replacement Therapy on Blood Pressure in Adult Male Participants With Hypogonadism (clinicaltrials.gov) - P4; N=729; Recruiting; Sponsor: Endo Pharmaceuticals

Clinical • New P4 trial

A new 2% testosterone gel formulation: a comparison with currently available topical preparations. (PubMed, Andrology) - "...Approved testosterone topical formulations include Tostrex(Tostran, Fortesta), Androgel(Testogel), Testimand Axiron(solution), which have a favourable efficacy profile and positively impacted patient-reported outcome(s)...This product comes with a metered dose dispenser and a cap applicator that allows a hands-free application for precise dispensing and application. The present article provides a comprehensive review of pharmacokinetic, tolerability and safety profile of the testosterone gels available in the market along with the new 2% testosterone gel, Testavan."

Journal • Review • Biosimilar

The Effect of Testosterone Topical Solution in Hypogonadal Men With Suboptimal Response to a Topical Testosterone Gel. (PubMed, Am J Mens Health) - "After treatment (or testosterone normalization), energy level improved in 75% of subjects and sexual drive improved in 70%. Topical 2% testosterone solution is a safe and effective treatment for HGN men who have had a suboptimal response to previous treatment with topical testosterone gels."

Journal